About: Gene therapy of cancer with tumour cells carrying inserted genes for co-stimulatory and cytokine molecules.

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About: Gene therapy of cancer with tumour cells carrying inserted genes for co-stimulatory and cytokine molecules. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=IZ3516
Description	Předmětem řešení projektu je využít přenosu klonovaných genů pro kostimulační molekuly typu B7(CD80,CD86) do nádorové TRA+ buňky,současně s transfekcí cDNA pro lymfokiny TH1 typu, k přípravě geneticky pozměněných buněčných preparátů.
Title	Gene therapy of cancer with tumour cells carrying inserted genes for co-stimulatory and cytokine molecules. (en) Genetické přístupy v imunoterapii zhoubných nádorů.
skos:notation	IZ3516
http://linked.open...avai/cep/aktivita	http://linked.opendata.cz/resource/domain/vavai/aktivita/IZ
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/IZ3516/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/IZ3516/celkoveNaklady
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	354788
http://linked.open...ai/cep/hlavniObor	FD - Onkologie a hematologie
http://linked.open.../cep/klicovaSlova	imunita,lymfokiny,molekuly CD 80,přenos genu (en)
http://linked.open...ep/partnetrHlavni	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	13 (xsd:int)
http://linked.open...enychVysledkuVRIV	13 (xsd:int)
http://linked.open...iciPoslednihoRoku	1998
http://linked.open...atUdajeProjZameru	1998
http://linked.open...usZobrazovaneFaze	DRRVK
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...tniCyklusProjektu	ZBK
http://linked.open.../cep/klicoveSlovo	imunita lymfokiny molekuly CD 80
is http://linked.open...vavai/riv/projekt of	Recombinant interleukin-2 acts as an adjuvant and helps to increase the efficacy of tumour vaccines. Treatment of transplanted spontaneous rat T-cell leukaemia with local administration of recombinant murine interleukin-2. Use of cryopreserved lymphocytes for assessment of the immunological effects of interferon therapy in renal cell carcinoma patients. Tumour inhibitory effects of plasmid DNA. Tumour vaccines expressing IL-2, CD80, and IL-2 plus CD80 gene. Immunogenicity, immunosensitivity and cell surface adhesiveness of tumour vaccines carrying an inserted CD80 gene. Irradiated IL-2-gene-modified plasmacytoma vaccines are more efficient than live vaccines. CD80 and IL-2 signals cooperate in the regression of tumors transplanted in congetally athymic mice. Interleukin 2 gene therapy of residual disease in mice carrying tumours induced by HPV 16. IL-2 gene-modified tumour vaccines: monitoring of IL-2 levels in serum and peritoneal cavity of vaccinated mice. Genetically modified tumour vaccines: insertion of the IL-2 gene downregulates tumorigenicity more efficiently than insertion of the CD80 gene. CTLL assay: comparison of two methods for IL-2 determination. Genetically Modified Tumour Vaccines Carrying Inserted Genes for Immunoregulatory Molecules.
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/IZ3516/1996/ico%3A68378050 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/IZ3516/1996/ico%3A75010330 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/IZ3516/1997/ico%3A68378050 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/IZ3516/1997/ico%3A75010330 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/IZ3516/1998/ico%3A68378050

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