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Description
  • This project covers a rational design, preparation, characterization and application of modified gold nanoparticles (GNPs). The synthesized chemically modified GNPs will be used for the separation purposes, specifically in capillary electrophoresis (CE) and capillary electrochromatography (CEC). For the immobilization of the structurally specific selectors on the GNP surfaces an electrostatic interaction as well as covalent coupling will be employed. A detailed characterization of the modified GNPs by various physico-chemical methods will precede their practical utilization in CE and CEC. The following classes of important biologically and pharmacologically active substances will be in the centre of our separation interest: chiral compounds (amino acids derivatives and potentially new drugs), glycosylated and phosphorylated peptides and proteins. (en)
  • Příprava a využití modifikovaných částic zlata v separačních technikách, především v kapilární elektroforéze a kapilární elektrochromatografii, pro dělení chirálních sloučenin a glykosylovaných a fosforylovaných peptidů a bílkovin.
Title
  • The utilization of gold nanoparticles in capillary electrophoresis and capillary electrochromatography (en)
  • Využití nanočástic zlata v kapilární elektroforéze a kapilární elektrochromatografii
skos:notation
  • GA203/09/0675
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  • nanočástice zlata, kapilarní elektroforéza, kapilární elektrochromatografie, chirální separace, glyk (en)
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  • Řešení projektu proběhlo výtečně, jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
  • The project was excellent, both in terms of expertise and in terms of disbursement of funds. (en)
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http://linked.open.../cep/klicoveSlovo
  • chirální separace
  • kapilarní elektroforéza
  • kapilární elektrochromatografie
  • nanočástice zlata
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