About: Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization.

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About: Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=7E09031
Description	Stem cells offer a promising avenue to therapy for a wide range of complaints. However, for this potential to be realized, a consistent and plentiful supply of well-characterised stem cells is essential. There has been relatively little progress in the development of new culture technologies for the large-scale manufacture of mesenchymal stem cells (MSCs). There are no standards for characterisation, isolation or identification of MSCs from any tissue, nor are there standard protocols for differentiation of MSCs to various lineages. Additionally, surface markers used for MSC characterization lack specificity and cryopreservation protocols are not standardized. PurStem will: - Identify the MSC “receptome” and, - Use this repertoire of growth factor receptors to, - Develop novel serum-free media for MSC production. (en) Stem cells offer a promising avenue to therapy for a wide range of complaints. However, for this potential to be realized, a consistent and plentiful supply of well-characterised stem cells is essential. There has been relatively little progress in the development of new culture technologies for the large-scale manufacture of mesenchymal stem cells (MSCs). There are no standards for characterisation, isolation or identification of MSCs from any tissue, nor are there standard protocols for differentiation of MSCs to various lineages. Additionally, surface markers used for MSC characterization lack specificity and cryopreservation protocols are not standardized. PurStem will: - Identify the MSC “receptome” and, - Use this repertoire of growth factor receptors to, - Develop novel serum-free media for MSC production.
Title	Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization. (en) Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization.
skos:notation	7E09031
http://linked.open...avai/cep/aktivita	Subvention of the projects of the Seventh Framework Programme of the European Community for research, technological development including demonstration activities (FP7) according to the Czech law 171/2007 Sb.
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/7E09031/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/7E09031/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2012-07-12 (xsd:date)
http://linked.open...i/cep/druhSouteze	RP - Spolufinancování programu ES
http://linked.open...ep/duvernostUdaju	C - Předmět podléhá obchodnímu tajemství (§17 až 20 Obchodního zákoníku), ale některé údaje jsou upraveny tak, aby byly zveřejnitelné
http://linked.open.../cep/fazeProjektu	91908213
http://linked.open...ai/cep/hlavniObor	EA - Morfologické obory a cytologie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open...vai/cep/kategorie	AP - Aplikovaný výzkum
http://linked.open.../cep/klicovaSlova	Stem cells; mesenchymal stem cells; serum-free cultivation; differentiation; phenotypic analysis (en)
http://linked.open...ep/partnetrHlavni	Lékařská fakulta v Hradci Králové
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	0 (xsd:int)
http://linked.open...enychVysledkuVRIV	0 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-03-10 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/3096%2F2010-32
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-10-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	EC - Imunologie
http://linked.open...ep/zahajeniReseni	2009-11-01 (xsd:date)
http://linked.open...jektu+dodavatelem	Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider. (en) Hodnocení výsledků řešení ministerstvo neprovádí, neboť podmínkou podpory je, že uchazeč byl vybrán mezinárodním poskytovatelem v souladu s pravidly příslušného programu. Projekt je hodnocen až po jeho schválení mezinárodním poskytovatelem. (cs)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open...n/vavai/cep/vyzva	http://linked.opendata.cz/resource/domain/vavai/cep/vyzva/FP7-Health-2009-two-stage
http://linked.open.../cep/klicoveSlovo	Stem cells differentiation mesenchymal stem cells serum-free cultivation
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E09031/2009/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E09031/2010/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E09031/2011/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E09031/2012/orjk%3A11150

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