About: Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assay developers, aims at developing quality guidelines for molecular in vitro diagnostics and to standardise the pre-analytical workflow in related procedures. Regarding the second point, SPIDIA aims at developing modern pre-analytical tools for diagnostics improving the stabilisation, handling and study of free biomolecules within blood, plasma, serum, tissues and tumours. Recent discoveries have revealed that RNA, DNA or proteins, released from pathological sites, like tumour cells or Alzheimer’s disease (AD) brain lesions, into the blood or as a secondary blood based response to the disease can serve (en) In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assay developers, aims at developing quality guidelines for molecular in vitro diagnostics and to standardise the pre-analytical workflow in related procedures. Regarding the second point, SPIDIA aims at developing modern pre-analytical tools for diagnostics improving the stabilisation, handling and study of free biomolecules within blood, plasma, serum, tissues and tumours. Recent discoveries have revealed that RNA, DNA or proteins, released from pathological sites, like tumour cells or Alzheimer’s disease (AD) brain lesions, into the blood or as a secondary blood based response to the disease can serve (cs)
Title	Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics (en) Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics (cs)
http://linked.open...vai/cislo-smlouvy	http://linked.opendata.cz/resource/domain/vavai/cep/smlouva/1086/2011-321
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http://linked.open...n/vavai/kategorie	http://linked.opendata.cz/resource/domain/vavai/cep/kategorie/1
http://linked.open...vai/klicova-slova	Standards; pre-analytical phase; in vitro diagnostics; molecular diagnostics; diagnostic tools; biomarkers; biomedical research; blood sample; tumour sample; tissue sample; quality assurance; sample collection; sample handling; sample stabilisation (en)
http://linked.open...avai/konec-reseni	2012-09-30 (xsd:date)
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is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2009/7E09019/ico-86652036 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2010/7E09019/ico-86652036 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2011/7E09019/ico-86652036 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2012/7E09019/ico-86652036 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2013/7E09019/ico-86652036

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