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rdf:type
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Description
| - The main objectives of the workshop were: - to present %22in use%22 experience of the pharmaceutical industry with the 3T3 Neutral Red Uptake Phototoxicity Test (3T3 NRU-PT), - to discuss why it differs from the results in the original validation exercise, - to discuss technical issues and consider ways to improve the usability of the 3T3 NRU-PT for (non-topical) pharmaceuticals, e.g., by modifying the threshold of chemical light absorption to trigger photo-toxicological testing, and by modifying technical aspects of the assay, or adjusting the criteria used to classify a positive response.
- The main objectives of the workshop were: - to present %22in use%22 experience of the pharmaceutical industry with the 3T3 Neutral Red Uptake Phototoxicity Test (3T3 NRU-PT), - to discuss why it differs from the results in the original validation exercise, - to discuss technical issues and consider ways to improve the usability of the 3T3 NRU-PT for (non-topical) pharmaceuticals, e.g., by modifying the threshold of chemical light absorption to trigger photo-toxicological testing, and by modifying technical aspects of the assay, or adjusting the criteria used to classify a positive response. (en)
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Title
| - The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop
- The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop (en)
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skos:prefLabel
| - The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop
- The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop (en)
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skos:notation
| - RIV/75010330:_____/12:00009764!RIV13-MZ0-75010330
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/75010330:_____/12:00009764
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - phototoxicity; in vitro; in vivo; testing; workshop (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Regulatory toxicology and pharmacology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Nakamura, K.
- Jírová, Dagmar
- Alépée, R.
- Barroso, J.
- Bauer, D.
- Ceridono, M.
- Corvi, R.
- DeSmedt, A.
- Fellows, M. D.
- Frank Nash, J.
- Gibbs, N. K.
- Heisler, E.
- Jacobs, A.
- Jones, D.
- Kandárová, H.
- Kasper, P.
- Kinyamu Akunda, J.
- Kreysa, J.
- Krul, C.
- Learn, D.
- Liebsch, M.
- Lynch, A. M.
- Muster, W.
- Pfannenbecker, U.
- Phillips, G.
- Robles, C.
- Rogiers, V.
- Tellner, P.
- Vohr, H. W.
- Wattrelos, O.
- Wilcox, P.
- Woods, J.
- Wändel Liminga, U.
- Zuang, V.
- van de Water, F.
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.yrtph.2012.06.001
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