About: Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Committee accepted the program of chemical safety in October 2003 called REACH, meaning %22Registration, Evaluation, Authorization of Chemicals%22. The protection of health of nature, including human beings, against harmful effects of chemicals is a goal of these programs. The development and research on new chemicals can become, however, cheaper than their testing and registration. The aim of effort of the present is, thus, to develop and to use alternative methods of testing toxic and adverse effects of chemicals, which would be cheaper and more informative than traditional tests with experimental animals. QSAR models are mathematical equations which make it possible to calculate (in silico methods) a magnitude of a biological, both pharmacological and toxicological, effects of chemicals using knowledge of their chemical constitution. Committee accepted the program of chemical safety in October 2003 called REACH, meaning %22Registration, Evaluation, Authorization of Chemicals%22. The protection of health of nature, including human beings, against harmful effects of chemicals is a goal of these programs. The development and research on new chemicals can become, however, cheaper than their testing and registration. The aim of effort of the present is, thus, to develop and to use alternative methods of testing toxic and adverse effects of chemicals, which would be cheaper and more informative than traditional tests with experimental animals. QSAR models are mathematical equations which make it possible to calculate (in silico methods) a magnitude of a biological, both pharmacological and toxicological, effects of chemicals using knowledge of their chemical constitution. (en)
Title	Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms (en)
skos:prefLabel	Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms (en)
skos:notation	RIV/75010330:_____/08:00007983!RIV10-MZ0-75010330
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA203/06/1265), P(GA305/03/1169), P(NJ7435), P(NR8780)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Pokorná, Adéla Rucki, Marián Hanzlíková, Iveta Tichý, Miloň Uzlová, Rút Tumová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní zdravotní ústav, příspěvková organizace
http://linked.open...dnocenehoVysledku	354846
http://linked.open...ai/riv/idVysledku	RIV/75010330:_____/08:00007983
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	binary mixtures; QSAR; acute toxicity (en)
http://linked.open.../riv/klicoveSlovo	binary mixtures QSAR acute toxicity
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[379924184C53]
http://linked.open...i/riv/nazevZdroje	Interdisciplinary toxicology
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Relationship between quantitative composition and acute toxicity of binary and ternary mixtures. Acute toxicity of binary and ternary mixtures of chemicals - QSAR analysis Models in risk assessment of chemical mixtures - a use of QSAR analysis Hazard identification of chemical mixtures - techniques of matematical statistics.
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	1
http://linked.open...iv/tvurceVysledku	Pokorná, Adéla Hanzlíková, Iveta Rucki, Marián Tichý, Miloň Tumová, Jana Uzlová, Rút
issn	1337-6853
number of pages	3 (xsd:int)

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