About: The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats.

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About: The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://imbm.fbmi.cvut.cz/soubory/sbornik.pdf
Description	Chitosan (CS) is a functional linear polysaccharide, which is prepared by partial N-deacetylation of chitin. Chitooligosaccharides (COS) can be produced by hydrolysis of CS. They exhibit various types of the potent biological activities useful for medical applications and health care. The changes in the bacterial population, followed by the shifts in the produced bacterial metabolites can significantly alter condition in gastrointestinal tract. In this in vivo study we modulated the changes of fecal bacteria population in healthy rats (groups: control, CS and COS) during administration of CS/COS. PCR-DGGE analysis was used to detect possible changes in bacterial population. The phylogenetic tree was also constructed. For the quantification of total and selected bacterial DNA was used real-time PCR analysis. CS/COS changed the composition of microbial ecosystem of gastrointestinal tract of healthy rats. Chitosan (CS) is a functional linear polysaccharide, which is prepared by partial N-deacetylation of chitin. Chitooligosaccharides (COS) can be produced by hydrolysis of CS. They exhibit various types of the potent biological activities useful for medical applications and health care. The changes in the bacterial population, followed by the shifts in the produced bacterial metabolites can significantly alter condition in gastrointestinal tract. In this in vivo study we modulated the changes of fecal bacteria population in healthy rats (groups: control, CS and COS) during administration of CS/COS. PCR-DGGE analysis was used to detect possible changes in bacterial population. The phylogenetic tree was also constructed. For the quantification of total and selected bacterial DNA was used real-time PCR analysis. CS/COS changed the composition of microbial ecosystem of gastrointestinal tract of healthy rats. (en)
Title	The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. (en)
skos:prefLabel	The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. (en)
skos:notation	RIV/68407700:21460/11:00192486!RIV12-MSM-21460___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(EE.2.3.20.0092)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Jarošíková, Taťána
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta biomedicínského inženýrství
http://linked.open...dnocenehoVysledku	196200
http://linked.open...ai/riv/idVysledku	RIV/68407700:21460/11:00192486
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	chitosan; fecal microbiota; PCR analysis (en)
http://linked.open.../riv/klicoveSlovo	PCR analysis fecal microbiota chitosan
http://linked.open...ontrolniKodProRIV	[2D28CDA31B20]
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	BIO-XUV Research Team Advancement at FBME CTU
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Bureš, M. Jarošíková, Taťána Koppová, I. Šimůnek, J.
http://localhost/t...ganizacniJednotka	21460

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