About: Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aggregation of the high-affinity IgE receptor (Fc epsilon RI) on the plasma membrane of mast cells and basophils initiates signaling events leading to a rapid release of preformed inflammatory mediators from secretory granules, and overall changes in cell morphology. Mast cell activation also causes reorganization of cytoskeletal components associated with membrane ruffling, spreading, and migration. Here we describe methods used for visualization of mast cell cytoskeleton, focusing on its two major components, microfilaments and microtubules, and their changes after cell triggering. Aggregation of the high-affinity IgE receptor (Fc epsilon RI) on the plasma membrane of mast cells and basophils initiates signaling events leading to a rapid release of preformed inflammatory mediators from secretory granules, and overall changes in cell morphology. Mast cell activation also causes reorganization of cytoskeletal components associated with membrane ruffling, spreading, and migration. Here we describe methods used for visualization of mast cell cytoskeleton, focusing on its two major components, microfilaments and microtubules, and their changes after cell triggering. (en)
Title	Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation (en)
skos:prefLabel	Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation (en)
skos:notation	RIV/68378050:_____/14:00442474!RIV15-GA0-68378050
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GA14-00703S), P(GA14-09807S), P(GA204/09/1777), P(GBP302/12/G101), P(KAN200520701), P(LC545), P(LD12073), P(LD13015)
http://linked.open...iv/cisloPeriodika	September 2014
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Dráber, Pavel Dráber, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	28261
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/14:00442474
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mast cells; plasma membrane; actin (en)
http://linked.open.../riv/klicoveSlovo	actin plasma membrane mast cells
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[13C1B09A1D14]
http://linked.open...i/riv/nazevZdroje	Methods in Molecular Biology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Microtubules in activated mast cells - targets for innovative therapies Signální dráhy v chemotaxi žírných buněk Functional Organisation of the Cell Nano-PCR - ultrasensitive test for detection of specific proteins in body fluids Membrane signalosomes of mast cells and basophils - targets for innovative therapies Molecular mechanisms of signaling through leukocyte receptors their role in health and disease. Analysis of signaling assemblies containing gamma-tubulin Proteiny ORMDL rodiny v signalizaci žírných buněk
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	1220
http://linked.open...iv/tvurceVysledku	Dráber, Pavel Dráber, Petr
http://linked.open...ain/vavai/riv/wos	000345968400015
issn	1064-3745
number of pages	19 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/978-1-4939-1568-2

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