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rdf:type
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Description
| - Oči zvířat se liší z anatomického hlediska. Proto se předpokládalo, že vznikly nezávisle několikrát v průběhu evoluce. Objev genu Pax6 zhruba před deseti lety ale všechny tyto argumenty zpochybnil. Od té doby se objevilo více důkazů pro opakované použití genu Pax6 a některých dalších regulátorů používaných pro genetický program vývoje oka. Nedávný výzkum ukázal, že i některé další geny rodiny Pax hrají klíčovou roli v morfogenezi oka. (cs)
- Animal eyes with widely different anatomical designs have long been thought to arise independently, multiple times during evolution. This view was challenged about a decade ago by the landmark discoveries that Pax6, a highly conserved transcription factor, plays a key role in eye morphogenesis in both flies and mammals. Since then, more evidence has emerged in favour of the redeployment of Pax6 and some other developmental control genes within the genetic program underlying eye formation throughout the animal kingdom. Recent work has indicated that other members of the Pax gene family play a pivotal role in eye morphogenesis. The Eye gone gene regulates eye growth in Drosophila, whereas the PaxB gene is implicated in visual system development in jellyfish, the most basal organism possessing eyes.
- Animal eyes with widely different anatomical designs have long been thought to arise independently, multiple times during evolution. This view was challenged about a decade ago by the landmark discoveries that Pax6, a highly conserved transcription factor, plays a key role in eye morphogenesis in both flies and mammals. Since then, more evidence has emerged in favour of the redeployment of Pax6 and some other developmental control genes within the genetic program underlying eye formation throughout the animal kingdom. Recent work has indicated that other members of the Pax gene family play a pivotal role in eye morphogenesis. The Eye gone gene regulates eye growth in Drosophila, whereas the PaxB gene is implicated in visual system development in jellyfish, the most basal organism possessing eyes. (en)
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Title
| - Pax genes in eye development and evolution
- Geny Pax ve vývoji oka a v evoluci (cs)
- Pax genes in eye development and evolution (en)
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skos:prefLabel
| - Pax genes in eye development and evolution
- Geny Pax ve vývoji oka a v evoluci (cs)
- Pax genes in eye development and evolution (en)
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skos:notation
| - RIV/68378050:_____/05:00022522!RIV06-AV0-68378050
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0520), P(GA204/04/1358), Z(AV0Z5052915)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/68378050:_____/05:00022522
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - paxpax; eye development; evolution (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Current Opinion in Genetics & Development
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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