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  • Here, we have performed a preliminary mapping of serotonergic processes and serotonin-lA (5-HT(1A)) receptors in thoracic and lumbar segments of the human spinal cord. 5-HT profiles in human spinal cord are present in the ventral horn, surrounding motoneurons, and also contact their presumptive dendrites at lumbar level. 5-HT(1A) receptors are present in the same area, but are more densely expressed at lumbar level. These findings pave the way for local specific therapies involving cellular and/or pharmacological tools targeting the serotonergic system.
  • Here, we have performed a preliminary mapping of serotonergic processes and serotonin-lA (5-HT(1A)) receptors in thoracic and lumbar segments of the human spinal cord. 5-HT profiles in human spinal cord are present in the ventral horn, surrounding motoneurons, and also contact their presumptive dendrites at lumbar level. 5-HT(1A) receptors are present in the same area, but are more densely expressed at lumbar level. These findings pave the way for local specific therapies involving cellular and/or pharmacological tools targeting the serotonergic system. (en)
Title
  • Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
  • Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord (en)
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  • Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
  • Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord (en)
skos:notation
  • RIV/68378041:_____/11:00368699!RIV12-AV0-68378041
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/09/1696), P(GAP304/11/0184), Z(AV0Z50390703)
http://linked.open...iv/cisloPeriodika
  • -
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
  • Rodriguez Arellano, Jose Julio
http://linked.open.../riv/druhVysledku
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  • 186225
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  • RIV/68378041:_____/11:00368699
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  • genito-urinary tract; locomotion; nociceptive pathway (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [F61725A5965B]
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  • Cell Death & Disease
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  • 2
http://linked.open...iv/tvurceVysledku
  • Bauchet, L.
  • Boniface, G.
  • Gerber, Y. N.
  • Hugnot, J. P.
  • Lonjon, N.
  • Perrin, F. E.
  • Privat, A. M.
  • Rodriguez Arellano, Jose Julio
  • Teigell, M.
http://linked.open...ain/vavai/riv/wos
  • 000296587500007
http://linked.open...n/vavai/riv/zamer
issn
  • 2041-4889
number of pages
http://bibframe.org/vocab/doi
  • 10.1038/cddis.2011.98
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