About: Is there a declining trend in ovarian function among infertility clinic patients?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. In a retrospective study, we analysed a large body of data from women, 20-40 years of age, undergoing IVF/ICSI treatment between 1995 and 2008. We defined ovarian function using five variables: basal FSH level, estradiol (E2) level on the day of HCG administration, dose of gonadotrophins used for ovarian stimulation, number of retrieved oocytes and dose of gonadotrophins per oocyte. Controlling simultaneously for temporal changes in patient age and stimulation protocol, we applied generalized additive models to describe the temporal trends. The results are indicative of a small, but detectable decrease in ovarian function over a period of 14 years, which is not causally related to the ageing population. We examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. In a retrospective study, we analysed a large body of data from women, 20-40 years of age, undergoing IVF/ICSI treatment between 1995 and 2008. We defined ovarian function using five variables: basal FSH level, estradiol (E2) level on the day of HCG administration, dose of gonadotrophins used for ovarian stimulation, number of retrieved oocytes and dose of gonadotrophins per oocyte. Controlling simultaneously for temporal changes in patient age and stimulation protocol, we applied generalized additive models to describe the temporal trends. The results are indicative of a small, but detectable decrease in ovarian function over a period of 14 years, which is not causally related to the ageing population. (en)
Title	Is there a declining trend in ovarian function among infertility clinic patients? Is there a declining trend in ovarian function among infertility clinic patients? (en)
skos:prefLabel	Is there a declining trend in ovarian function among infertility clinic patients? Is there a declining trend in ovarian function among infertility clinic patients? (en)
skos:notation	RIV/68081766:_____/10:00337970!RIV11-AV0-68081766
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(AV0Z60930519), Z(MSM6198959212)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Tkadlec, Emil
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav biologie obratlovců AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	264980
http://linked.open...ai/riv/idVysledku	RIV/68081766:_____/10:00337970
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ovarian function; decrease; infertility; IVF (en)
http://linked.open.../riv/klicoveSlovo	infertility ovarian function IVF decrease
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[6BB59C7D65CC]
http://linked.open...i/riv/nazevZdroje	Human Reproduction
http://linked.open...in/vavai/riv/obor	FK
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Tkadlec, Emil Hladíková, B. Sobek Jr., A. Sobek, A.
http://linked.open...ain/vavai/riv/wos	000272929600019
http://linked.open...n/vavai/riv/zamer	Biodiverzita a ekologie obratlovců: Strategie ochrany a využívání přírodních populací Life-history strategies of animals: proximate and ultimate mechanisms
issn	0268-1161
number of pages	6 (xsd:int)

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