About: Interferon-inducible protein 16: Insight into the interaction with tumor suppressor p53     Goto   Sponge   Distinct   Permalink

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Description
  • Here, we report the crystal structures of both HIN-A and HIN-B domains of IFI16 determined at 2.0 and 2.35 Ao resolution, respectively. We show that both HIN domains of IFI16 are capable of enhancing p53-DNA complex formation and transcriptional activation via distinctive means.
  • Here, we report the crystal structures of both HIN-A and HIN-B domains of IFI16 determined at 2.0 and 2.35 Ao resolution, respectively. We show that both HIN domains of IFI16 are capable of enhancing p53-DNA complex formation and transcriptional activation via distinctive means. (en)
Title
  • Interferon-inducible protein 16: Insight into the interaction with tumor suppressor p53
  • Interferon-inducible protein 16: Insight into the interaction with tumor suppressor p53 (en)
skos:prefLabel
  • Interferon-inducible protein 16: Insight into the interaction with tumor suppressor p53
  • Interferon-inducible protein 16: Insight into the interaction with tumor suppressor p53 (en)
skos:notation
  • RIV/68081707:_____/11:00366123!RIV12-AV0-68081707
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GAP301/10/1211), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 205348
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/11:00366123
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • p53; HIN domain; p53-DNA complex (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [B41122617A2D]
http://linked.open...i/riv/nazevZdroje
  • Structure
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 19
http://linked.open...iv/tvurceVysledku
  • Brázda, Václav
  • Arrowsmith, Ch. H.
  • Chirgadze, N.Y.
  • Duan, S.
  • Lam, R.
  • Liao, J.C.C.
  • Ma, J.
  • Ravichandran, M.
  • Tempel, W.
  • Wang, Y.-X.
  • Xiao, T.
  • Zuo, X.
http://linked.open...ain/vavai/riv/wos
  • 000288689400016
http://linked.open...n/vavai/riv/zamer
issn
  • 0969-2126
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.str.2010.12.015
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