About: Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells

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About: Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Effects of indirubin, a putative novel ligand of aryl hydrocarbon receptor, had been tested in an in vitro model of rat oval cells, and compared with the effects of model toxic ligand, TCDD. We observed dose-sependent differences in indirubin action on AhR activation and on expression of selected genes known to be regulated by AhR/ARNT signaling pathway. Effects of indirubin, a putative novel ligand of aryl hydrocarbon receptor, had been tested in an in vitro model of rat oval cells, and compared with the effects of model toxic ligand, TCDD. We observed dose-sependent differences in indirubin action on AhR activation and on expression of selected genes known to be regulated by AhR/ARNT signaling pathway. (en)
Title	Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells (en)
skos:prefLabel	Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells (en)
skos:notation	RIV/68081707:_____/11:00359013!RIV12-AV0-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA524/06/0517), Z(AV0Z50040507), Z(AV0Z50040702), Z(MZE0002716202)
http://linked.open...iv/cisloPeriodika	1-3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kozubík, Alois Vondráček, Jan Procházková, Jiřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	194582
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/11:00359013
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	indirubin; aryl hydrocarbon receptor; plakoglobin (en)
http://linked.open.../riv/klicoveSlovo	aryl hydrocarbon receptor indirubin plakoglobin
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[EF82034616EE]
http://linked.open...i/riv/nazevZdroje	Toxicology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	279
http://linked.open...iv/tvurceVysledku	Kozubík, Alois Machala, M. Procházková, Jiřina Vondráček, Jan
http://linked.open...ain/vavai/riv/wos	000287109900018
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions Animal disease research, prevention and food chain protection
issn	0300-483X
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.tox.2010.10.003

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