About: Label-free voltammetric detection of single-nucleotide mismatches recognized by the protein MutS

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	MutS protein recognizes mispaired and unpaired bases in dsDNA. In this work was used electrochemical detection of MutS at carbon paste electrode in combination with double surface technique (MutS bind to DNA heteroduplex at the surface of magnetic beads) for detection of single base mismatch in 30- and 95-mer DNA duplexes. MutS protein recognizes mispaired and unpaired bases in dsDNA. In this work was used electrochemical detection of MutS at carbon paste electrode in combination with double surface technique (MutS bind to DNA heteroduplex at the surface of magnetic beads) for detection of single base mismatch in 30- and 95-mer DNA duplexes. (en) Protein MutS rozeznává špatně spárované a nespárované báze v dvojřetězcové DNA. V této práci bylo použito elektrochemické detekce MutS na uhlíkové pastové elektrodě v kombinaci s dvoupovrchovou technikou (MutS se váže na DNA heteroduplex na povrchu magnetické kuličky) pro detekci záměny jedné báze v 30- a 95-merních DNA duplexech. (cs)
Title	Label-free voltammetric detection of single-nucleotide mismatches recognized by the protein MutS %22Label free%22 voltametrická detekce záměny jednoho nukleotidu rozpoznané proteinem MutS (cs) Label-free voltammetric detection of single-nucleotide mismatches recognized by the protein MutS (en)
skos:prefLabel	Label-free voltammetric detection of single-nucleotide mismatches recognized by the protein MutS %22Label free%22 voltametrická detekce záměny jednoho nukleotidu rozpoznané proteinem MutS (cs) Label-free voltammetric detection of single-nucleotide mismatches recognized by the protein MutS (en)
skos:notation	RIV/68081707:_____/07:00081562!RIV07-AV0-68081707
http://linked.open.../vavai/riv/strany	259;270
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1H-PK/42), P(GA203/04/1325), P(GA301/07/0490), P(LC06035), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Cahová, Kateřina Paleček, Emil Fojta, Miroslav Masařík, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	430365
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/07:00081562
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	point mutation; MutS; protein electrochemistry (en)
http://linked.open.../riv/klicoveSlovo	point mutation MutS protein electrochemistry
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[1D3C0D77BE2C]
http://linked.open...i/riv/nazevZdroje	Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Research and development of a new type of electrochemical biosensor for the detection of nucleotide sequences in DNA and of genotoxic agents in the environment. Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine. Protein and DNA-modified electrodes. New tools for biomedicine New approaches in development of electrochemical sensors for DNA damage
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	388
http://linked.open...iv/tvurceVysledku	Fojta, Miroslav Kizek, R. Masařík, Michal Paleček, Emil Cahová, Kateřina
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems
issn	1618-2642
number of pages	12 (xsd:int)

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