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Description
| - The presence of truncated form of cyclin A2 has been reported in various murine cell lines and tissues. In this paper it was shown that while undifferentiated proliferating mouse embryonic stem cells express low levels of this truncated cyclin A2, cells that are induced to differentiate remarkably increase its synthesis. Importantly, the expression pattern of truncated cyclin A2 was the same in p27 -/- ES cells as in the wild-type ES cells. Thus, it suggests that p27 is not necessary for the proteolytic cleavage of cyclin A2 and that this post-translational modification correlates with differentiation.
- The presence of truncated form of cyclin A2 has been reported in various murine cell lines and tissues. In this paper it was shown that while undifferentiated proliferating mouse embryonic stem cells express low levels of this truncated cyclin A2, cells that are induced to differentiate remarkably increase its synthesis. Importantly, the expression pattern of truncated cyclin A2 was the same in p27 -/- ES cells as in the wild-type ES cells. Thus, it suggests that p27 is not necessary for the proteolytic cleavage of cyclin A2 and that this post-translational modification correlates with differentiation. (en)
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Title
| - The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells.
- The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells. (en)
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skos:prefLabel
| - The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells.
- The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells. (en)
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skos:notation
| - RIV/67985904:_____/03:21033079!RIV/2004/GA0/A21004/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA523/00/0780), P(LN00A065), Z(AV0Z5039906), Z(AV0Z5045916)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985904:_____/03:21033079
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - mouse embryonic stem cell (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Biochemical and Biophysical Research Communications
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...nichUcastnikuAkce
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bryja, Vítězslav
- Dvořák, Petr
- Hampl, Aleš
- Motlík, Jan
- Anger, Martin
- Kubelka, Michal
- Carrington, M.
- Jirmanová, L.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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