About: Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects     Goto   Sponge   Distinct   Permalink

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Description
  • Differentiation and metabolism of adipose tissue are modulated by thyroid hormones (THs), but relatively little is known about the metabolism of THs in this tissue. Our results document increased D1 gene expression and activity in adipose tissue of obese humans and suggest a role of 3,5,30-triiodo-L-thyronine formed by D1 in response to leptin in the modulation of adipose tissue metabolism
  • Differentiation and metabolism of adipose tissue are modulated by thyroid hormones (THs), but relatively little is known about the metabolism of THs in this tissue. Our results document increased D1 gene expression and activity in adipose tissue of obese humans and suggest a role of 3,5,30-triiodo-L-thyronine formed by D1 in response to leptin in the modulation of adipose tissue metabolism (en)
Title
  • Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects
  • Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects (en)
skos:prefLabel
  • Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects
  • Type I iodothyronine 5-deiodinase mRNA and activity is increased in adipose tissue of obese subjects (en)
skos:notation
  • RIV/67985823:_____/12:00377147!RIV13-AV0-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(OC08008), Z(AV0Z50110509), Z(MSM0021622413)
http://linked.open...iv/cisloPeriodika
  • 2
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http://linked.open...dnocenehoVysledku
  • 175530
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/12:00377147
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • adipose tissue; thyroid hormones; deiodinases; tissue expression; enzyme activity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [A656C12D052E]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Obesity
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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  • 36
http://linked.open...iv/tvurceVysledku
  • Kopecký, Jan
  • Jílková, Zuzana
  • Fernández-Real, J. M.
  • Moreno-Navarrete, J. M.
  • Ortega, F. J.
  • Pavelka, S.
  • Rodriguez-Hermosa, J. I.
http://linked.open...ain/vavai/riv/wos
  • 000300321600019
http://linked.open...n/vavai/riv/zamer
issn
  • 0307-0565
number of pages
http://bibframe.org/vocab/doi
  • 10.1038/ijo.2011.101
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