About: Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats

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About: Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Anticonvulsant and neuroprotective effect of (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate, agonist for group II metabotropic glutamate receptors, was substantially reduced when given after the onset of seizures induced in immature rats by homocysteic acid. The severity of seizures, changes of brain energy metabolites and neuronal damage of hippocampus and thalamus were influenced only partially Anticonvulsant and neuroprotective effect of (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate, agonist for group II metabotropic glutamate receptors, was substantially reduced when given after the onset of seizures induced in immature rats by homocysteic acid. The severity of seizures, changes of brain energy metabolites and neuronal damage of hippocampus and thalamus were influenced only partially (en)
Title	Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats (en)
skos:prefLabel	Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats (en)
skos:notation	RIV/67985823:_____/09:00327874!RIV10-AV0-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA206/93/0666), P(GA304/07/1137), P(GA309/05/2015), P(GA309/08/0292), Z(AV0Z50110509), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Haugvicová, Renata Otáhal, Jakub Druga, Rastislav Tsenov, Grygoriy Folbergrová, Jaroslava
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	334734
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/09:00327874
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DL-homocysteic acid-induced seizures; posttreatment with 2R; 4R-APDC; partial protection (en)
http://linked.open.../riv/klicoveSlovo	DL-homocysteic acid-induced seizures 4R-APDC partial protection posttreatment with 2R
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[B45394DF0D31]
http://linked.open...i/riv/nazevZdroje	Brain Research
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of oxidative stress in brain injury following status epilepticus induced in immature rats Study of potential protective effects of selected drugs on the development of epileptogenesis following status epilepticus induced in immature rats Damage of the basal ganglia in LiCl/pilocarpine model of temporal lobe epilepsy in immature rats Modernization of the Culture Collection Operation to Rescue the Genofond of Fungi
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	1273
http://linked.open...iv/tvurceVysledku	Otáhal, Jakub Druga, Rastislav Tsenov, Grygoriy Folbergrová, Jaroslava Haugvicová, Renata
http://linked.open...ain/vavai/riv/wos	267516600016
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Microorganisms in Research and Biotechnology
issn	0006-8993
number of pages	11 (xsd:int)

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