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  • As it is known that several non-aromatic substituted oxime derivatives function as vasorelaxant NO donors in vitro, we studied blood pressure changes elicited by administration of some of them to conscious chronically catheterized Wistar rats after acute blockade of NO synthesis. Substances with hydrophilic character were effective to induce vasorelaxation, whereas less hydrophilic or slightly hydrophobic substances were ineffective
  • As it is known that several non-aromatic substituted oxime derivatives function as vasorelaxant NO donors in vitro, we studied blood pressure changes elicited by administration of some of them to conscious chronically catheterized Wistar rats after acute blockade of NO synthesis. Substances with hydrophilic character were effective to induce vasorelaxation, whereas less hydrophilic or slightly hydrophobic substances were ineffective (en)
  • Jelikož je známo, že několik nearomatických substituovaných derivátů působí jako vazorelaxační donory NO, sledovali jsme změny krevního tlaku vyvolané podáním některých z nich bdělým chronicky kanylovaným Wistar potkanům po akutní blokádě syntézy NO. Látky s hydrofilním charakterem byly účinné při vyvolání vazorelaxace, zatímco méně hydrofilní nebo mírně hydrofobní byly neúčinné (cs)
Title
  • Vasorelaxant activity of some oxime derivatives
  • Vasorelaxant activity of some oxime derivatives (en)
  • Vazorelaxační aktivita některých oximových derivátů (cs)
skos:prefLabel
  • Vasorelaxant activity of some oxime derivatives
  • Vasorelaxant activity of some oxime derivatives (en)
  • Vazorelaxační aktivita některých oximových derivátů (cs)
skos:notation
  • RIV/67985823:_____/07:00089191!RIV08-AV0-67985823
http://linked.open.../vavai/riv/strany
  • 122;126
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0510), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 1-3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 457572
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/07:00089191
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • vasorelaxation; Non-aromatic substituted oxime derivates (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [11543CFB266F]
http://linked.open...i/riv/nazevZdroje
  • European Journal of Pharmacology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 575
http://linked.open...iv/tvurceVysledku
  • Kuneš, Jaroslav
  • Pintérová, Mária
  • Zicha, Josef
  • Dobešová, Zdenka
  • Entlicher, G.
  • Chalupský, K.
  • Jaroš, F.
  • Straka, T.
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-2999
number of pages
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