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rdf:type
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Description
| - We found that in SHR harboring the deletion variant of Cd36 (fatty acid transporter), transgenic expression of wild type Cd36 in modest amounts ameliorates defects in fatty acid metabolism, glucose tolerance, and insulin stimulated glucose uptake in muscle and fat tissue and second, exerts little or no effect on blood pressure. In conclusion, the current studies provide definitive evidence that mutant Cd36 is a QTL with major effect on insulin action, glucose tolerance, and serum fatty acid levels in the SHR/NIH strains.
- We found that in SHR harboring the deletion variant of Cd36 (fatty acid transporter), transgenic expression of wild type Cd36 in modest amounts ameliorates defects in fatty acid metabolism, glucose tolerance, and insulin stimulated glucose uptake in muscle and fat tissue and second, exerts little or no effect on blood pressure. In conclusion, the current studies provide definitive evidence that mutant Cd36 is a QTL with major effect on insulin action, glucose tolerance, and serum fatty acid levels in the SHR/NIH strains. (en)
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Title
| - Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats.
- Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. (en)
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skos:prefLabel
| - Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats.
- Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. (en)
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skos:notation
| - RIV/67985823:_____/01:20010171!RIV/2003/AV0/A20003/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA301/00/1636), P(GV204/98/K015), P(LN00A079), Z(AV0Z5011922), Z(AV0Z5052915)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/67985823:_____/01:20010171
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Cd36 (fatty acid transporter) (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...ocetUcastnikuAkce
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http://linked.open...nichUcastnikuAkce
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kazdová, L.
- Křen, Vladimír
- Kurtz, T. W.
- Landa, Vladimír
- Pravenec, Michal
- Zídek, Václav
- Aitman, T. J.
- Musilová, Alena
- Abumrad, N. A.
- Glazier, A. M.
- Qi, N.
- Wang, J. M.
- Ibrahimi, A.
- St. Lezin, E. M.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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