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Description
| - Studie pojednává o schopnosti rTMS ovlivnit negativní příznaky schizofrenie. Do (N=1) studie byla zařazen pacient s diagnózou paranoidní schizofrenie, který byl po dobu třech týdnů léčen neúčinnou, sham stimulací a následující tři týdny skutečnou rTMS. byla užita vysokofrekvenční rTMS aplikovaná nad oblastí levého dorzolaterálního prefrontálního kortexu. Psychopatologie byla hodnocena před zahájem stimulační léčby, po ukončení neúčinné a skutečné rTMS. Skutečná rTMS oproti neúčinné výrazně více ovlivnila negativní příznaky schizofrenie. Vysokofrekvenční rTMS aplikovaná nad oblastí levého prefrontálního kortexu představuje možnost augmentace antipsychotik při léčbě negativních příznaků schizofrenie. (cs)
- The present trial was designed to investigate the influence of rTMS on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
- The present trial was designed to investigate the influence of rTMS on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia. (en)
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Title
| - Influencing negative symptoms of schizophrenia with repetitive transcranial magentic stimulation: a case study
- Influencing negative symptoms of schizophrenia with repetitive transcranial magentic stimulation: a case study (en)
- Ovlivnění negativních příznaků schizofrenie prostřednictvím repetitivní transkraniální magnetické stimulace: kazuistické sdělení (cs)
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skos:prefLabel
| - Influencing negative symptoms of schizophrenia with repetitive transcranial magentic stimulation: a case study
- Influencing negative symptoms of schizophrenia with repetitive transcranial magentic stimulation: a case study (en)
- Ovlivnění negativních příznaků schizofrenie prostřednictvím repetitivní transkraniální magnetické stimulace: kazuistické sdělení (cs)
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skos:notation
| - RIV/65269705:_____/07:#0000073!RIV08-MZ0-65269705
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/65269705:_____/07:#0000073
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - negative symptoms; schizophrenia; rTMS (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - AU - Australské společenství
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kašpárek, Tomáš
- Přikryl, Radovan
- Ustohal, Libor
- Češková, Eva
- Kučerová, Hana
- Skotáková, Simona
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issn
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number of pages
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