About: Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression ?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nejčastější změny nalezené u astrocytárních nádorů postihují 2 hlavní skupiny proteinů: proteiny podílející se na regulaci buněčného cyklu a proteiny uplatňující se v signálních drahách regulovaných růstovými faktory. Cílem naší práce bylo detekovat změny v expresi proteinů: nádorového supresoru PTEN, p53 a p21, GFAP. (cs) The most frequent alternations found in astrocytomas are two major groups of signaling proteins: the cell cycle and the growth factor-regulated signaling pathways. The aim of our study was to detect changes in expression of the following proteins: the tumor suppressors PTEN, p53, and p21. The most frequent alternations found in astrocytomas are two major groups of signaling proteins: the cell cycle and the growth factor-regulated signaling pathways. The aim of our study was to detect changes in expression of the following proteins: the tumor suppressors PTEN, p53, and p21. (en)
Title	Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression ? Mohou se změny signální dráhy PI3K/PKB/Akt a buněčného cyklu uplatnit v patogenezi a progresi astrocytárních nádorů ? (cs) Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression ? (en)
skos:prefLabel	Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression ? Mohou se změny signální dráhy PI3K/PKB/Akt a buněčného cyklu uplatnit v patogenezi a progresi astrocytárních nádorů ? (cs) Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression ? (en)
skos:notation	RIV/61989592:15110/07:00003935!RIV08-MZ0-15110___
http://linked.open.../vavai/riv/strany	334-341
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1A8244), P(NR7828), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Hlobilková, Alice Hamerlík, Petra EHRMANN, Jiří Krejčí, Veronika KOLÁŘ, Zdeněk Sedláková, Eva Bezděková, Michala KALA, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	415182
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/07:00003935
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Astrocytoma; PI3K/PKB/Akt pathway; cell cycle and immunohistochemistry (en)
http://linked.open.../riv/klicoveSlovo	PI3K/PKB/Akt pathway cell cycle and immunohistochemistry Astrocytoma
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[C79B9FB26484]
http://linked.open...i/riv/nazevZdroje	Neoplasma
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of expression of STAT, JAK and SOCS in glial tumors of brain and in carcinomas of breast and prostate gland. Correlation with grading, expression of steroid receptors and expression of proteins regulating cell cycle and apoptosis. Study of importance of proteins regulating PI3-K/PKB/Akt signaling pathway and cell cycle for glioblastoma pathogenesis
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Ehrmann, Jiří Krejčí, Veronika Kolář, Zdeněk Sedláková, Eva Kala, Miroslav Hlobilková, Alice Knížetová, Petra Kalita, O. Fiurášková, Michala
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0028-2685
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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