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  • Toxicita složek sedimentů kontaminovaných uhelnými kaly byla sledována v seríi experimentů. Reprodukční schopnosti blešivců Gammarus fossarum a předožábrého plže Potamopyrgus antipodarum byly ovlivněny po jejich laboratorní expozici uhelnými sediemnty z Karvinského uhelného regionu v severovýchodní části ČR. Extrakt sedimentů vykazuje prokazatelný efekt na plodnost P. antipodarum. Byla zjištěna vysoká dioxinová aktivita extraktu sedimentu a absence jeho účinku na estrogenové receptory při použití dvou vzorků buněk H4IIE.luc a MVLN. Výsledky napovídají, že složky uhelných kalů mohou vyvolávat endokrinní poruchy v in vivo a in vitro experimentech a mohou tedy představovat i chronický rizikový faktor vůči přírodě i obyvatelstvu. (cs)
  • Toxicity of compounds presented in sediment contaminated by waste coal has been examined in a set of experiments. Reproduction parameters of amphipod Gammarus fossarum and prosobranchian snail Potamopyrgus antipodarum were affected after laboratory exposures to contaminated coal sediments from Karviná mining area, northeastern Czech Republic. The sediment extract has elicited comparable effects on fecundity of P. antipodarum. High dioxin-like activity and no estrogen receptor mediated effects were determined in sediment extract using two in vitro bioassays with H4IIE.luc and MVLN cells. Our findings indicate that compounds of waste coal origin might evoke endocrine disruptive effects both in vitro and in vivo and they might represent chronic risks to wildlife and humans.
  • Toxicity of compounds presented in sediment contaminated by waste coal has been examined in a set of experiments. Reproduction parameters of amphipod Gammarus fossarum and prosobranchian snail Potamopyrgus antipodarum were affected after laboratory exposures to contaminated coal sediments from Karviná mining area, northeastern Czech Republic. The sediment extract has elicited comparable effects on fecundity of P. antipodarum. High dioxin-like activity and no estrogen receptor mediated effects were determined in sediment extract using two in vitro bioassays with H4IIE.luc and MVLN cells. Our findings indicate that compounds of waste coal origin might evoke endocrine disruptive effects both in vitro and in vivo and they might represent chronic risks to wildlife and humans. (en)
Title
  • Ecotoxicological evaluation of sediments contaminated by waste coal by in vivo and in vitro bioassays
  • Ecotoxicological evaluation of sediments contaminated by waste coal by in vivo and in vitro bioassays (en)
  • Ekotoxikologický rozbor sedimentů kontaminovaných uhelnými kaly na základě in vivo a in vitro metod (cs)
skos:prefLabel
  • Ecotoxicological evaluation of sediments contaminated by waste coal by in vivo and in vitro bioassays
  • Ecotoxicological evaluation of sediments contaminated by waste coal by in vivo and in vitro bioassays (en)
  • Ekotoxikologický rozbor sedimentů kontaminovaných uhelnými kaly na základě in vivo a in vitro metod (cs)
skos:notation
  • RIV/61988987:17310/06:A0800HP1!RIV08-GA0-17310___
http://linked.open.../vavai/riv/strany
  • 274;278
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  • P(GP525/05/P160)
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  • 472826
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  • RIV/61988987:17310/06:A0800HP1
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  • Coal sediments; sediemnt biotests; in vitro bioassays; AhR; ER; endocrine disruption (en)
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  • [E7C71BC2B67E]
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  • Ostrava
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  • Ostrava
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  • Scripta Facultatis Rerum Naturalium Universitatis Ostraviensis
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  • Bláha, Luděk
  • Giesy, John P.
  • Horká, Ivona
  • Ďuriš, Zdeněk
  • Triebskorn, Rita
  • Mazurová, Edita
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http://linked.open.../riv/zahajeniAkce
number of pages
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  • Repronis
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  • 80-7368-201-X
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  • 17310
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