| Attributes | Values |
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| rdf:type
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| Description
| - To study the structure–activity relationships of aromatic cytokinins, the cytokinin activity at both the receptor and cellular levels, as well as CDK inhibitory and anticancer properties of 38 6-benzylaminopurine (BAP) derivatives were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine with corresponding substituted benzylamines. The majority of synthesised derivatives exhibited high activity in all three of the cytokinin bioassays employed (tobacco callus, wheat senescence and Amaranthus bioassay). The highest activities were obtained in the senescence bioassay. For some compounds tested, significant differences of activity were found in the bioassays used, indicating that diverse recognition systems may operate and suggesting that it may be possible to modulate particular cytokinin-dependent processes with specific compounds. Position-specific steric and hydrophobic effects of different phenyl ring substituents on the variation of biological act...
- To study the structure–activity relationships of aromatic cytokinins, the cytokinin activity at both the receptor and cellular levels, as well as CDK inhibitory and anticancer properties of 38 6-benzylaminopurine (BAP) derivatives were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine with corresponding substituted benzylamines. The majority of synthesised derivatives exhibited high activity in all three of the cytokinin bioassays employed (tobacco callus, wheat senescence and Amaranthus bioassay). The highest activities were obtained in the senescence bioassay. For some compounds tested, significant differences of activity were found in the bioassays used, indicating that diverse recognition systems may operate and suggesting that it may be possible to modulate particular cytokinin-dependent processes with specific compounds. Position-specific steric and hydrophobic effects of different phenyl ring substituents on the variation of biological act... (en)
- Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells. (cs)
|
| Title
| - Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells
- Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells (en)
- Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells (cs)
|
| skos:prefLabel
| - Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells
- Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells (en)
- Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells (cs)
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| skos:notation
| - RIV/61389030:_____/06:00082763!RIV07-AV0-61389030
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| http://linked.open.../vavai/riv/strany
| |
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(GA203/04/1168), P(IBS4055304), Z(AV0Z50380511), Z(MSM 153100008)
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| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/61389030:_____/06:00082763
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - 6-Benzylaminopurine; Cytokinin; Receptor (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Bioorganic Medical Chemistry
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Doležal, Karel
- Holub, Jan
- Kryštof, Vladimír
- Schmülling, T.
- Strnad, Miroslav
- Spíchal, Lukáš
- Popa, Igor
- Lenobel, René
- Fojtíková, M.
|
| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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