About: Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.

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About: Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A search among analogues of anti-CDK purines led to the identification of substituted pyrazolo[4,3-d]pyrimidines as novel inhibitors of CDK1/cyclin B. Some of these derivatives also show antiproliferative activity on cancer cell line K-562, thus may find an application as anticancer agents. A search among analogues of anti-CDK purines led to the identification of substituted pyrazolo[4,3-d]pyrimidines as novel inhibitors of CDK1/cyclin B. Some of these derivatives also show antiproliferative activity on cancer cell line K-562, thus may find an application as anticancer agents. (en)
Title	Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. (en)
skos:prefLabel	Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. (en)
skos:notation	RIV/61389030:_____/03:56033102!RIV/2004/GA0/A56004/N
http://linked.open.../vavai/riv/strany	2989ů2992
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/02/0475), P(GA303/02/0875), P(KJB4038301), Z(AV0Z5038910)
http://linked.open...iv/cisloPeriodika	18
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Moravec, Jiří Havlíček, Libor Kryštof, Vladimír Strnad, Miroslav Lenobel, René Moravcová, Daniela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	624326
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/03:56033102
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pyrazolo[4,3-d]pyrimidines; CDK1/cyclin B; anticancer agents (en)
http://linked.open.../riv/klicoveSlovo	anticancer agents 3-d]pyrimidines Pyrazolo[4 CDK1/cyclin B
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[7174171FFBD1]
http://linked.open...i/riv/nazevZdroje	Bioorganic and Medicinal Chemistry Letters
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of new generation of cyclin-dependent kinase inhibitors: structure-activity relationships, molecular and in vitro mechanisms of action Purine inhibitors of cyclin-dependent kinases as anticancer and antimitotic compounds Pyrazolo[4,3-d]pyrimidines as a new generation of anticytokinines and inhibitors of cyclin-dependent kinases
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Havlíček, Libor Kryštof, Vladimír Moravec, Jiří Strnad, Miroslav Lenobel, René Moravcová, Daniela
http://linked.open...n/vavai/riv/zamer	Physiological and genetical bases of plant development, cell cycle, morphogenesis, stress reactions and biotechnologies. Genome organisation and function
issn	0960-894X
number of pages	4 (xsd:int)

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