Attributes | Values |
---|
rdf:type
| |
Description
| - Tato práce charakterizuje vliv mutací I47A a I54V v HIV-1 protease na sníženou citlivost k inbitoru lopinaviru a vzužívá enzymatické a strukturální metody a take metody molekulové dynamiky. Výsledky práce nám mohou pomoci porozumět lépe vývoji resistence k proteasovým inhibitorům. (cs)
- This paper characterizes the influence of I47A and I54V mutations on the susceptibility to protease inhibitor lopinavir using enzymatic, structural and molecular dynamics analysis. The results may help us understanding development of the resistance to HIV protease inhibitors.
- This paper characterizes the influence of I47A and I54V mutations on the susceptibility to protease inhibitor lopinavir using enzymatic, structural and molecular dynamics analysis. The results may help us understanding development of the resistance to HIV protease inhibitors. (en)
|
Title
| - Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir
- Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir (en)
- Enzymatická a strukturální charakterizace mutace I47A podílející se na snížšné citlivosti k HIV proteasovému inhibitoru lopinaviru (cs)
|
skos:prefLabel
| - Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir
- Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir (en)
- Enzymatická a strukturální charakterizace mutace I47A podílející se na snížšné citlivosti k HIV proteasovému inhibitoru lopinaviru (cs)
|
skos:notation
| - RIV/61388963:_____/08:00312673!RIV09-MZ0-61388963
|
http://linked.open...avai/riv/aktivita
| |
http://linked.open...avai/riv/aktivity
| - P(1M0508), P(NR8571), R, Z(AV0Z40550506), Z(AV0Z50520514)
|
http://linked.open...iv/cisloPeriodika
| |
http://linked.open...vai/riv/dodaniDat
| |
http://linked.open...aciTvurceVysledku
| |
http://linked.open.../riv/druhVysledku
| |
http://linked.open...iv/duvernostUdaju
| |
http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/61388963:_____/08:00312673
|
http://linked.open...riv/jazykVysledku
| |
http://linked.open.../riv/klicovaSlova
| - HIV protease inhibitors; antiviral resistance development; X-ray structure; molecular recognition; enzyme kinetics (en)
|
http://linked.open.../riv/klicoveSlovo
| |
http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
http://linked.open...ontrolniKodProRIV
| |
http://linked.open...i/riv/nazevZdroje
| |
http://linked.open...in/vavai/riv/obor
| |
http://linked.open...ichTvurcuVysledku
| |
http://linked.open...cetTvurcuVysledku
| |
http://linked.open...vavai/riv/projekt
| |
http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Brynda, Jiří
- Konvalinka, Jan
- Kožíšek, Milan
- Lepšík, Martin
- Prejdová, Jana
- Řezáčová, Pavlína
- Machala, L.
- Grantz Šašková, Klára
- Kagan, R. M.
|
http://linked.open...ain/vavai/riv/wos
| |
http://linked.open...n/vavai/riv/zamer
| |
issn
| |
number of pages
| |