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  • The first electron transfer to radiosensitizer etanidazole (ETN) and ETN radical anion formation in buffered aqueous media was studied by means of voltammetric techniques and Electrochemical Impendance Spectroscopy (EIS). The heterogeneous electron transfer rate constant for the first reduction of ETN (radical anion production) k0 for the redox couple and so called E1,7 potential were calculated. The obtained values of k0 and E1,7 potential indicate that ETN compared to some other possible chemical radiosensitizers requires lower energy to accept the first electron during metabolic pathway.
  • The first electron transfer to radiosensitizer etanidazole (ETN) and ETN radical anion formation in buffered aqueous media was studied by means of voltammetric techniques and Electrochemical Impendance Spectroscopy (EIS). The heterogeneous electron transfer rate constant for the first reduction of ETN (radical anion production) k0 for the redox couple and so called E1,7 potential were calculated. The obtained values of k0 and E1,7 potential indicate that ETN compared to some other possible chemical radiosensitizers requires lower energy to accept the first electron during metabolic pathway. (en)
Title
  • Electrochemistry of selected radiosenzitizer-etanidazole
  • Electrochemistry of selected radiosenzitizer-etanidazole (en)
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  • Electrochemistry of selected radiosenzitizer-etanidazole
  • Electrochemistry of selected radiosenzitizer-etanidazole (en)
skos:notation
  • RIV/61388955:_____/10:00343502!RIV11-GA0-61388955
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  • P(GP203/09/P502), P(LC510), P(OC 140), Z(AV0Z40400503)
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  • 256716
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  • RIV/61388955:_____/10:00343502
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  • etanidazole; cyclic voltammetry; radiosensitizers; electrochemical impendance spectroscopy (en)
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  • [CE060C311813]
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  • Gál, Miroslav
  • Hromadová, Magdaléna
  • Híveš, J.
  • Kolivoška, Viliam
  • Pospíšil, Lubomír
  • Sokolová, Romana
  • Bulíčková, Jana
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number of pages
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  • BEST servis
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  • 978-80-254-6710-7
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