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Description
  • Mason-Pfizer monkey virus encodes an aspartic protease (M-PMV PR), which is essential for the maturation of the virion particles by processing viral protein precursors yielding fully functional structural proteins and enzymes. The overall fold of all known retroviral proteases is quite conservative despite rather large varieties of their amino acid sequences. However, Mason-Pfizer Monkey Virus protease exists in three active forms, which is a feature making this enzyme unique within the this family. In vivo Mason-Pfizer Monkey Virus protease occurs as a 17 kDa (per monomer) molecule. In vitro it undergoes a rapid self-processing at the C-terminus yielding 13 kDa and finally 12 kDa forms [1]. We will present backbone resonance assignment and secondary structure identification of shortest 12 kDa form of protease from Mason-Pfizer Monkey Virus [2].
  • Mason-Pfizer monkey virus encodes an aspartic protease (M-PMV PR), which is essential for the maturation of the virion particles by processing viral protein precursors yielding fully functional structural proteins and enzymes. The overall fold of all known retroviral proteases is quite conservative despite rather large varieties of their amino acid sequences. However, Mason-Pfizer Monkey Virus protease exists in three active forms, which is a feature making this enzyme unique within the this family. In vivo Mason-Pfizer Monkey Virus protease occurs as a 17 kDa (per monomer) molecule. In vitro it undergoes a rapid self-processing at the C-terminus yielding 13 kDa and finally 12 kDa forms [1]. We will present backbone resonance assignment and secondary structure identification of shortest 12 kDa form of protease from Mason-Pfizer Monkey Virus [2]. (en)
Title
  • Backbone resonance assignment of protease from Mason-Pfizer monkey virus
  • Backbone resonance assignment of protease from Mason-Pfizer monkey virus (en)
skos:prefLabel
  • Backbone resonance assignment of protease from Mason-Pfizer monkey virus
  • Backbone resonance assignment of protease from Mason-Pfizer monkey virus (en)
skos:notation
  • RIV/60461373:22640/01:00004693!RIV/2004/GA0/226404/N
http://linked.open.../vavai/riv/strany
  • 291-292
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA203/00/1241)
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  • 3
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  • 674124
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  • RIV/60461373:22640/01:00004693
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  • NMR spectroscopy, protease, Mason-Pfizer virus (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [0F6081461997]
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  • Journal of Biomolecular NMR
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 20
http://linked.open...iv/tvurceVysledku
  • Pichová, Iva
  • Hrabal, Richard
  • Veverka, Václav
  • Bauerová, Helena
  • Zábranský, Aleš
issn
  • 0925-2738
number of pages
http://localhost/t...ganizacniJednotka
  • 22640
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