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rdf:type
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Description
| - Retroviruses are subject of intensive studies not only in context with AIDS pandemia and oncogenic effect on several organisms including human. The understanding of retroviral capsid assembly mechanisms and nucleic acids incorporation could significantly contribute to further use of these systems for therapeutic purposes. Our research is focused on study of forming of Mason-Pfizer monkey virus (M-PMV) immature capsids in vitro. M PMV as the prototype of D-type retrovirus is an excellent model for assembly studies. These retroviruses are characterized by the assembly of intracytoplasmic capsids, which make their way to the plasma membrane and are released by budding. Gag polyproteins of all retroviruses contain domains corresponding to the structural proteins which are important for driving the assembly process, namely matrix (MA), capsid (CA) and nucleocapsid (NC) proteins.We have found specific conditions under which we can prepare properly assembled capsids in vitro from structural polyprotein Gag a
- Retroviruses are subject of intensive studies not only in context with AIDS pandemia and oncogenic effect on several organisms including human. The understanding of retroviral capsid assembly mechanisms and nucleic acids incorporation could significantly contribute to further use of these systems for therapeutic purposes. Our research is focused on study of forming of Mason-Pfizer monkey virus (M-PMV) immature capsids in vitro. M PMV as the prototype of D-type retrovirus is an excellent model for assembly studies. These retroviruses are characterized by the assembly of intracytoplasmic capsids, which make their way to the plasma membrane and are released by budding. Gag polyproteins of all retroviruses contain domains corresponding to the structural proteins which are important for driving the assembly process, namely matrix (MA), capsid (CA) and nucleocapsid (NC) proteins.We have found specific conditions under which we can prepare properly assembled capsids in vitro from structural polyprotein Gag a (en)
- Skládání MPMV kapsid in vitro (cs)
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Title
| - Assembly of M-PMV retroviral capsids in vitro
- Assembly of M-PMV retroviral capsids in vitro (en)
- Skládání MPMV kapsid in vitro (cs)
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skos:prefLabel
| - Assembly of M-PMV retroviral capsids in vitro
- Assembly of M-PMV retroviral capsids in vitro (en)
- Skládání MPMV kapsid in vitro (cs)
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skos:notation
| - RIV/60461373:22330/04:00012742!RIV/2005/MSM/223305/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22330/04:00012742
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - CA-NC protein;in vitro assembly (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Proceedings of the XIX. meeting of czech and slovak societies for biochemistry and molecular biology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Ruml, Tomáš
- Rumlová, Michaela
- Ulbrich, Pavel
- Haubová, Šárka
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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issn
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number of pages
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http://purl.org/ne...btex#hasPublisher
| - Univerzita Palackého v Olomouci
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http://localhost/t...ganizacniJednotka
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