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rdf:type
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Description
| - Rapid and correct production of generic solid dosage forms requires a large amount of analytical data and conclusions. Modern analytical techniques have a good resolution and accuray and allow obtaining a lot of information about the original products. Scanning electron microscopy (SEM) is used for observation infrared (FTIR) spectroscopy mapping allows determining the distribution and characterization of individual components in a solid dosage form. However, the samples prepared by common way, using scalpel or tablet splitter, are not good enough. It was the reason for development of a new and better method of sample preparation, which uses microtome. Well-prepared samples analyzed by SEM and FTIR mapping allow to determine a solid dosage form formulation, excipient content and distribution of excipient and active pharmaceutical ingredient.
- Rapid and correct production of generic solid dosage forms requires a large amount of analytical data and conclusions. Modern analytical techniques have a good resolution and accuray and allow obtaining a lot of information about the original products. Scanning electron microscopy (SEM) is used for observation infrared (FTIR) spectroscopy mapping allows determining the distribution and characterization of individual components in a solid dosage form. However, the samples prepared by common way, using scalpel or tablet splitter, are not good enough. It was the reason for development of a new and better method of sample preparation, which uses microtome. Well-prepared samples analyzed by SEM and FTIR mapping allow to determine a solid dosage form formulation, excipient content and distribution of excipient and active pharmaceutical ingredient. (en)
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Title
| - A new way of solid dosage form samples preparation for SEM and FTIR using microtome
- A new way of solid dosage form samples preparation for SEM and FTIR using microtome (en)
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skos:prefLabel
| - A new way of solid dosage form samples preparation for SEM and FTIR using microtome
- A new way of solid dosage form samples preparation for SEM and FTIR using microtome (en)
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skos:notation
| - RIV/60461373:22310/13:43895356!RIV14-MSM-22310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22310/13:43895356
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - surface; solid dosage form; scanning electron microscopy; microtome; FTIR mapping; Cut (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Pharmaceutical Development and Technology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kratochvíl, Bohumil
- Grünwaldová, Veronika
- Šimek, Michal
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.3109/10837450.2013.788515
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http://localhost/t...ganizacniJednotka
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