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Description
  • Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment.
  • Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment. (en)
Title
  • Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides
  • Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides (en)
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  • Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides
  • Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides (en)
skos:notation
  • RIV/60162694:G44__/13:43874937!RIV14-MZ0-G44_____
http://linked.open...avai/riv/aktivita
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  • I, P(LH13009), P(NT12062)
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  • 14
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  • 100407
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  • RIV/60162694:G44__/13:43874937
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  • toxicity; oxime; protection; reactivator; organophosphate; antidote; treatment; prophylaxis; poisoning; pesticides; nerve agents; butyrylcholinesterase; Acetylcholinesterase (en)
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  • 13
http://linked.open...iv/tvurceVysledku
  • Kuča, Kamil
  • Musílek, Kamil
  • Pohanka, Miroslav
  • Žďárová Karasová, Jana
  • Jun, Daniel
  • Soukup, Ondřej
http://linked.open...ain/vavai/riv/wos
  • 000328088300011
issn
  • 1389-5575
number of pages
http://bibframe.org/vocab/doi
  • 10.2174/13895575113136660108
http://localhost/t...ganizacniJednotka
  • G44
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