About: The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery

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About: The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.springer.com/?SGWID=0-102-24-0-0&sortOrder=relevance&searchType=EASY_CDA&searchScope=onlinecontent&queryText=the+effect+of+somatostatin+and+its+analogs+in+the+prevention+of+pancreatic+fistula+after+elective+pancreatic+surgery
Description	Background: The prophylactic use of somatostatin and its analogs has been suggested to lower the rate of pancreatic fistula. The aim of this review is to discuss the results of published randomized trials and meta-analyses studying the effect of somatostatin and its analogs. Methods: We performed a Medline search for prospective randomized trials, systematic reviews and meta-analyses with regard to the prophylactic use of somatostatin and its analogs. Results: Eleven randomized trials and six meta-analyses were identified. The randomized trials differ in terms of study designs, diagnosis, operative procedures, drug dosage, time of administration, and the pancreatic fistula definition; therefore, it is advisable to carefully interpret the results of the individual randomized trials. Conclusion: The routine administration of somatostatin and its analogs in elective pancreatic surgery cannot be recommended. However, selective administration is advisable in cases which carry significantly higher risk of developing pancreatic fistula. Background: The prophylactic use of somatostatin and its analogs has been suggested to lower the rate of pancreatic fistula. The aim of this review is to discuss the results of published randomized trials and meta-analyses studying the effect of somatostatin and its analogs. Methods: We performed a Medline search for prospective randomized trials, systematic reviews and meta-analyses with regard to the prophylactic use of somatostatin and its analogs. Results: Eleven randomized trials and six meta-analyses were identified. The randomized trials differ in terms of study designs, diagnosis, operative procedures, drug dosage, time of administration, and the pancreatic fistula definition; therefore, it is advisable to carefully interpret the results of the individual randomized trials. Conclusion: The routine administration of somatostatin and its analogs in elective pancreatic surgery cannot be recommended. However, selective administration is advisable in cases which carry significantly higher risk of developing pancreatic fistula. (en)
Title	The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery (en)
skos:prefLabel	The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery (en)
skos:notation	RIV/60162694:G44__/12:43874685!RIV13-MO0-G44_____
http://linked.open...avai/riv/aktivita	I V
http://linked.open...avai/riv/aktivity	I, V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Šubrt, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	133267
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/12:43874685
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	postoperative complications; pancreatic fistula; pancreatic surgery; octreotide; somatostatin (en)
http://linked.open.../riv/klicoveSlovo	somatostatin pancreatic fistula octreotide postoperative complications pancreatic surgery
http://linked.open...odStatuVydavatele	AT - Rakouská republika
http://linked.open...ontrolniKodProRIV	[16CFBDC4B98C]
http://linked.open...i/riv/nazevZdroje	European Surgery
http://linked.open...in/vavai/riv/obor	FJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Ferko, Alexander Jon, Bohumil Čečka, Filip Šubrt, Zdeněk
http://linked.open...ain/vavai/riv/wos	000304610000008
issn	1682-8631
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s10353-011-0612-z
http://localhost/t...ganizacniJednotka	G44

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