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  • Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity, its inhibition and reactivation is widely studied for elucidation of action of toxic compounds such as nerve agents as well as for the effect of antidotes (especially reactivators). AChE activity can be determined biochemically (homogenates of tissues, parts of organs not differing in the fine localization of the activity) or histochemically (allowing to localize the activity/inhibition/reactivation), both in vitro and in vivo. It is demonstrated that complementary use of these two methods can contribute to more precise localization of the the target. Moreover, both methods correlate well and are used for elucidation of the action of nerve agents. Other morphological results (microvascularization, morphological changes) are also of interest. Other factors influencing the activity of both enzymes are described.
  • Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity, its inhibition and reactivation is widely studied for elucidation of action of toxic compounds such as nerve agents as well as for the effect of antidotes (especially reactivators). AChE activity can be determined biochemically (homogenates of tissues, parts of organs not differing in the fine localization of the activity) or histochemically (allowing to localize the activity/inhibition/reactivation), both in vitro and in vivo. It is demonstrated that complementary use of these two methods can contribute to more precise localization of the the target. Moreover, both methods correlate well and are used for elucidation of the action of nerve agents. Other morphological results (microvascularization, morphological changes) are also of interest. Other factors influencing the activity of both enzymes are described. (en)
Title
  • Different factors influencing acetylcholinesterase (butyrylcholinesterase) activity in the organism
  • Different factors influencing acetylcholinesterase (butyrylcholinesterase) activity in the organism (en)
skos:prefLabel
  • Different factors influencing acetylcholinesterase (butyrylcholinesterase) activity in the organism
  • Different factors influencing acetylcholinesterase (butyrylcholinesterase) activity in the organism (en)
skos:notation
  • RIV/60162694:G44__/09:00002120!RIV10-MO0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MO0FVZ0000501)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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  • 310471
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/09:00002120
http://linked.open...riv/jazykVysledku
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  • butyrylcholinesterase; nerve agents, acetylcholinesterase, inhibition, different factors (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [8CCCC536548B]
http://linked.open...i/riv/mistoVydani
  • Kerala
http://linked.open...i/riv/nazevZdroje
  • Central and peripheral nervous system: effects of highly toxic organophosphates and their antidotes
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Bajgar, Jiří
  • Kassa, Jiří
  • Kuča, Kamil
  • Fusek, Josef
  • Jun, Daniel
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Research Signpost
https://schema.org/isbn
  • 978-81-308-0331-9
http://localhost/t...ganizacniJednotka
  • G44
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