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rdf:type
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Description
| - Oba nově vyvinuté oximy (K074, K075) stejně jako obidoxim jsou schopny redukovat cyklosarinem indukovanou akutní neurotoxicitu, ale jejich neuroprotektivní účinnost je signifikantně nižší ve srovnání s oximem HI-6. Proto je oxim HI-6 stále nejvhodnějším oximem pro antidotní terapii akutní otravy cyklosarinem vzhledem k jeho neuroprotektivní a reaktivační účinnosti. (cs)
- Both newly developed oximes (K074, K075) as well as obidoxime are also able to counteract cyclosarin-induced acute neurotoxicity but their neuroprotective potency is significantly lower compared to the oxime HI-6. Therefore, the oxime HI-6 is still the most suitable oxime for the antidotal treatment of acute poisonings with cyclosarin due to its neuroprotective as well as reactivating efficacy.
- Both newly developed oximes (K074, K075) as well as obidoxime are also able to counteract cyclosarin-induced acute neurotoxicity but their neuroprotective potency is significantly lower compared to the oxime HI-6. Therefore, the oxime HI-6 is still the most suitable oxime for the antidotal treatment of acute poisonings with cyclosarin due to its neuroprotective as well as reactivating efficacy. (en)
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Title
| - Vyhodnocení neuroprotektivního účinku nově vyvinutých oximů (K074, K075) a v současnosti dostupných oximů (obidoxim, HI-6) na potkanech otrávených cyklosarinem (cs)
- The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats
- The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats (en)
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skos:prefLabel
| - Vyhodnocení neuroprotektivního účinku nově vyvinutých oximů (K074, K075) a v současnosti dostupných oximů (obidoxim, HI-6) na potkanech otrávených cyklosarinem (cs)
- The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats
- The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats (en)
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skos:notation
| - RIV/60162694:G44__/07:00001761!RIV08-MO0-G44_____
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G44__/07:00001761
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - cyclosarin; atropine; K oximes; HI-6; obidoxime; functional observational battery (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Applied Toxicology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kassa, Jiří
- Karasová, Jana
- Vašina, Libor
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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