About: Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats     Goto   Sponge   Distinct   Permalink

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  • The replacement of dichloride anion by dimethanesulphonate anion in the oxime HI-6 does not influence the therapeutic and reactivating efficacy of the oxime HI-6 against nerve agents. In addition, the higher solubility and stability of HI-6 dimethanesulphonate in comparison with HI-6 dichloride makes possible to increase the dose and, thus, the effectiveness of the oxime HI-6 in the antidotal treatment of acute nerve agent poisonings.
  • The replacement of dichloride anion by dimethanesulphonate anion in the oxime HI-6 does not influence the therapeutic and reactivating efficacy of the oxime HI-6 against nerve agents. In addition, the higher solubility and stability of HI-6 dimethanesulphonate in comparison with HI-6 dichloride makes possible to increase the dose and, thus, the effectiveness of the oxime HI-6 in the antidotal treatment of acute nerve agent poisonings. (en)
Title
  • Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats
  • Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats (en)
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  • Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats
  • Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats (en)
skos:notation
  • RIV/60162694:G44__/07:00001760!RIV10-MO0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 414382
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/07:00001760
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • HI-6 dichloride; HI-6 dimethansulfonate; tabun; soman; cyclosarin; acetylcholinesterase (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [DF8A71F98FFC]
http://linked.open...i/riv/nazevZdroje
  • Basic and Clinical Pharmacology and Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 101
http://linked.open...iv/tvurceVysledku
  • Bajgar, Jiří
  • Kassa, Jiří
  • Kuča, Kamil
  • Jun, Daniel
http://linked.open...ain/vavai/riv/wos
  • 000249924900007
http://linked.open...n/vavai/riv/zamer
issn
  • 1742-7835
number of pages
http://localhost/t...ganizacniJednotka
  • G44
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