Attributes | Values |
---|
rdf:type
| |
Description
| - The oxime K005 [1,3-bis(2-hydroxyiminomethylpyridinium) propane dibromide] for the reactivation of the enzyme acetylcholinesterase (AChE) inhibited by cyclosarin and VX were tested. Its reactivation potency was not better in comparison with the currently used AChE reactivator - pralidoxime. On the other hand, the oxime K005 has its maximum reactivation ability at the concentration 10-4 M, which could be achieved for human use. The maximum concentration of pralidoxime was reached at the concentrations 10-1 M [for cyclosarin] and 10-3 M [for VX] but these concentrations are not available for the use in vivo.
- The oxime K005 [1,3-bis(2-hydroxyiminomethylpyridinium) propane dibromide] for the reactivation of the enzyme acetylcholinesterase (AChE) inhibited by cyclosarin and VX were tested. Its reactivation potency was not better in comparison with the currently used AChE reactivator - pralidoxime. On the other hand, the oxime K005 has its maximum reactivation ability at the concentration 10-4 M, which could be achieved for human use. The maximum concentration of pralidoxime was reached at the concentrations 10-1 M [for cyclosarin] and 10-3 M [for VX] but these concentrations are not available for the use in vivo. (en)
- 1,3-bis(2-hydroxyiminomethylpyridinium) propan jako potenciální reaktivátor acetylcholinesterázy inhibované nervově paralytickými látkami (cs)
|
Title
| - 1,3-bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents
- 1,3-bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents (en)
- 1,3-bis(2-hydroxyiminomethylpyridinium) propan jako potenciální reaktivátor acetylcholinesterázy inhibované nervově paralytickými látkami (cs)
|
skos:prefLabel
| - 1,3-bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents
- 1,3-bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents (en)
- 1,3-bis(2-hydroxyiminomethylpyridinium) propan jako potenciální reaktivátor acetylcholinesterázy inhibované nervově paralytickými látkami (cs)
|
skos:notation
| - RIV/60162694:G38__/04:00001077!RIV/2005/MO0/G38005/N
|
http://linked.open.../vavai/riv/strany
| |
http://linked.open...avai/riv/aktivita
| |
http://linked.open...avai/riv/aktivity
| |
http://linked.open...iv/cisloPeriodika
| |
http://linked.open...vai/riv/dodaniDat
| |
http://linked.open...aciTvurceVysledku
| |
http://linked.open.../riv/druhVysledku
| |
http://linked.open...iv/duvernostUdaju
| |
http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G38__/04:00001077
|
http://linked.open...riv/jazykVysledku
| |
http://linked.open.../riv/klicovaSlova
| - acetylcholinesterase;reactivation;inhibition;oximes;reactivator;pralidoxime;cyclosarin;VX;in vitro;K005;nerve agents;organophosphates (en)
|
http://linked.open.../riv/klicoveSlovo
| |
http://linked.open...odStatuVydavatele
| |
http://linked.open...ontrolniKodProRIV
| |
http://linked.open...i/riv/nazevZdroje
| - Acta Medica (Hradec Králové)
|
http://linked.open...in/vavai/riv/obor
| |
http://linked.open...ichTvurcuVysledku
| |
http://linked.open...cetTvurcuVysledku
| |
http://linked.open...vavai/riv/projekt
| |
http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Dohnal, Vlastimil
- Kuča, Kamil
|
issn
| |
number of pages
| |
http://localhost/t...ganizacniJednotka
| |