About: Bactosim - the bacterial simulator

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.slu.cz/su/slu/cz/projekty/webs/it4i
Description	The purpose of the conjugative simulator is to simulate the behavior of conjugation-based computing experiments within bacteria E. Coli. These experiments are based on interplay of three types of plasmids: pA, pB and pC. We use two strains of E. Coli: the producer strains which carry either the plasmid pA or pB, and the computing strain which originally carries the plasmid pC. Producer cells may contain different alleles of pA or pB. These plasmids are transferred to computing cells via the process of horizontal gene transfer so that most of the cells would end up containing three plasmids pA, pB and pC. The computing strain also contains a biochemical device called comparator. Its purpose is to evaluate whether the combination of alleles of pA and pB together with pC present in the cell satisfies certain pre-defined condition. In the negative case the comparator produces protein TetR which makes the plasmids pA and pB unstable. They are eventually lost and replaced by different alleles and the process is repeated. In the affirmative case the plasmids become stable and allowed to be replicated. The purpose of the conjugative simulator is to simulate the behavior of conjugation-based computing experiments within bacteria E. Coli. These experiments are based on interplay of three types of plasmids: pA, pB and pC. We use two strains of E. Coli: the producer strains which carry either the plasmid pA or pB, and the computing strain which originally carries the plasmid pC. Producer cells may contain different alleles of pA or pB. These plasmids are transferred to computing cells via the process of horizontal gene transfer so that most of the cells would end up containing three plasmids pA, pB and pC. The computing strain also contains a biochemical device called comparator. Its purpose is to evaluate whether the combination of alleles of pA and pB together with pC present in the cell satisfies certain pre-defined condition. In the negative case the comparator produces protein TetR which makes the plasmids pA and pB unstable. They are eventually lost and replaced by different alleles and the process is repeated. In the affirmative case the plasmids become stable and allowed to be replicated. (en)
Title	Bactosim - the bacterial simulator Bactosim - the bacterial simulator (en)
skos:prefLabel	Bactosim - the bacterial simulator Bactosim - the bacterial simulator (en)
skos:notation	RIV/47813059:19240/13:#0004808!RIV14-MSM-19240___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0070)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Sosík, Petr Beneš, David
http://linked.open.../riv/druhVysledku	R - Software
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...onomickeParametry	Volně šiřitelný software s licencí GNU GPL
http://linked.open...titaPredkladatele	Slezská univerzita v Opavě / Filozoficko-přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	62813
http://linked.open...ai/riv/idVysledku	RIV/47813059:19240/13:#0004808
http://linked.open...terniIdentifikace	Bactosim
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Bacterium; Conjugation; Simulator (en)
http://linked.open.../riv/klicoveSlovo	Conjugation Bacterium Simulator
http://linked.open...ontrolniKodProRIV	[B0CBA48A6637]
http://linked.open...in/vavai/riv/obor	IN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	IT4Innovations Centre of Excellence
http://linked.open...UplatneniVysledku	2013
http://linked.open...echnickeParametry	Simulace kolonie o velikosti až 1 mil. bakterií
http://linked.open...iv/tvurceVysledku	Sosík, Petr Beneš, David
http://linked.open...avai/riv/vlastnik	Slezská univerzita v Opavě
http://linked.open...itiJinymSubjektem	N - Nabytí licence není nutné (výsledek není licencován)
http://localhost/t...ganizacniJednotka	19240

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