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rdf:type
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Description
| - Eukaryotic genomes are rich in sequences capable of forming non-B DNA structures. These structures are expected to play important roles in natural regulatory processes at levels above those of individual genes, such as whole genome dynamics or chromatin organization, as well as in processes leading to the loss of these functions, such as cancer development. Recently, a number of authors have mapped the occurrence of potential quadruplex sequences in the human genome and found them to be associated with promoters. In this paper, we set out to map the distribution and characteristics of potential triplex-forming sequences in human genome DNA sequences. Using the R/Bioconductor package triplex, we found these sequences to be excluded from exons, while present mostly in a small number of repetitive sequence classes, especially short sequence tandem repeats (microsatellites), Alu and combined elements, such as SVA. We also introduce a novel way of classifying potential triplex sequences, using
- Eukaryotic genomes are rich in sequences capable of forming non-B DNA structures. These structures are expected to play important roles in natural regulatory processes at levels above those of individual genes, such as whole genome dynamics or chromatin organization, as well as in processes leading to the loss of these functions, such as cancer development. Recently, a number of authors have mapped the occurrence of potential quadruplex sequences in the human genome and found them to be associated with promoters. In this paper, we set out to map the distribution and characteristics of potential triplex-forming sequences in human genome DNA sequences. Using the R/Bioconductor package triplex, we found these sequences to be excluded from exons, while present mostly in a small number of repetitive sequence classes, especially short sequence tandem repeats (microsatellites), Alu and combined elements, such as SVA. We also introduce a novel way of classifying potential triplex sequences, using (en)
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Title
| - Uneven distribution of potential triplex sequences in the human genome: In silico study using the R/Bioconductor package triplex
- Uneven distribution of potential triplex sequences in the human genome: In silico study using the R/Bioconductor package triplex (en)
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skos:prefLabel
| - Uneven distribution of potential triplex sequences in the human genome: In silico study using the R/Bioconductor package triplex
- Uneven distribution of potential triplex sequences in the human genome: In silico study using the R/Bioconductor package triplex (en)
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skos:notation
| - RIV/00216305:26230/14:PU111943!RIV15-MSM-26230___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(ED1.1.00/02.0070), P(EE2.3.20.0189), S
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216305:26230/14:PU111943
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Human genome, DNA sequence, Non-B-DNA, Triplex, Bioconductor, Repetitive sequences, Mobile DNA, Lexicographically minimal rotation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Brázdová, Marie
- Lexa, Matej
- Martínek, Tomáš
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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number of pages
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http://bibframe.org/vocab/doi
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http://purl.org/ne...btex#hasPublisher
| - SciTePress - Science and Technology Publications
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https://schema.org/isbn
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http://localhost/t...ganizacniJednotka
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