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Description
| - Recent findings suggest that apoptotic protein apoptosis-inducing factor (AIF) may also play an important non-apoptotic function inside mitochondria. AIF was proposed to be an important component of respiratory chain complex I that is the major producer of superoxide radical. The possible role of AIF is still controversial. Superoxide production could be used as a valuable measure of complex I function, because the majority of superoxide is produced there. Therefore, we employed superoxide-specific mitochondrial fluorescence dye for detection of superoxide production. We studied an impact of AIF knockdown on function of mitochondrial complex I by analyzing superoxide production in selected cell lines.
- Recent findings suggest that apoptotic protein apoptosis-inducing factor (AIF) may also play an important non-apoptotic function inside mitochondria. AIF was proposed to be an important component of respiratory chain complex I that is the major producer of superoxide radical. The possible role of AIF is still controversial. Superoxide production could be used as a valuable measure of complex I function, because the majority of superoxide is produced there. Therefore, we employed superoxide-specific mitochondrial fluorescence dye for detection of superoxide production. We studied an impact of AIF knockdown on function of mitochondrial complex I by analyzing superoxide production in selected cell lines. (en)
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Title
| - Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I
- Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I (en)
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skos:prefLabel
| - Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I
- Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I (en)
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skos:notation
| - RIV/00216224:14330/12:00057522!RIV13-GA0-14330___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14330/12:00057522
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - superoxide; fluorescence microscopy; image analysis; mitochondria; telomerase (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - AR - Argentinská republika
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Matula, Pavel
- Procházková, Jiřina
- Kozubek, Michal
- Vařecha, Miroslav
- Cmarko, Dušan
- Páclová, Daniela
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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