About: Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention.     Goto   Sponge   Distinct   Permalink

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Description
  • Aim Randomized trials in ST elevation myocardial infarction (STEMI) showed improved early outcomes after primary percutaneous coronary intervention (p.PCI) compared with thrombolysis (TL). It is less known whether the early benefit is sustained during the long.term follow.up. Methods and results The PRAGUE 2 trial enrolled 850 STEMI patients presenting to community hospitals without cathlabs within 12 h of symptom onset. Patients were randomized into the groups , TL in community hospital (n = 421) and interhospital transfer for pPCI (n = 429). Follow up data were available in 416 (98.8%) patients in the TL group and 428 (99.8%) in the p.PCI group. At 5 year follow.up, the cumulative incidence of composite endpoint (death from any cause or recurrent infarction or stroke or revascularization) was 53% in TL patients compared with 40% in pPCI patients (HR 1.8; 95% CI 1.38 2.3; P < 0.001). The respective cumulative incidence of death from any cause was 23 and 19% (HR 1.34; 95% CI 0.99 to 1.82; P = 0.
  • Aim Randomized trials in ST elevation myocardial infarction (STEMI) showed improved early outcomes after primary percutaneous coronary intervention (p.PCI) compared with thrombolysis (TL). It is less known whether the early benefit is sustained during the long.term follow.up. Methods and results The PRAGUE 2 trial enrolled 850 STEMI patients presenting to community hospitals without cathlabs within 12 h of symptom onset. Patients were randomized into the groups , TL in community hospital (n = 421) and interhospital transfer for pPCI (n = 429). Follow up data were available in 416 (98.8%) patients in the TL group and 428 (99.8%) in the p.PCI group. At 5 year follow.up, the cumulative incidence of composite endpoint (death from any cause or recurrent infarction or stroke or revascularization) was 53% in TL patients compared with 40% in pPCI patients (HR 1.8; 95% CI 1.38 2.3; P < 0.001). The respective cumulative incidence of death from any cause was 23 and 19% (HR 1.34; 95% CI 0.99 to 1.82; P = 0. (en)
Title
  • Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention.
  • Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention. (en)
skos:prefLabel
  • Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention.
  • Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention. (en)
skos:notation
  • RIV/00216224:14110/07:00050942!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, N, Z(MSM0021620817)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 431428
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/07:00050942
http://linked.open...riv/jazykVysledku
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  • Myocardial infarction; Primary coronary intervention; Thrombolysis; Interhospital transport; Long-term outcome (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [2FD3AAF3070A]
http://linked.open...i/riv/nazevZdroje
  • European Heart Journal
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Aschermann, Michael
  • Groch, Ladislav
  • Novák, Martin
  • Pěnička, Martin
  • Widimsky, Petr
  • Bílková, Dana
  • Budesinsky, Tomas
  • Lanikova, Miroslava
  • Porizka, Vladimir
  • Zelizko, Michael
http://linked.open...ain/vavai/riv/wos
  • 000244960400011
http://linked.open...n/vavai/riv/zamer
issn
  • 0195-668X
number of pages
http://bibframe.org/vocab/doi
  • 10.1093/eurheartj/ehl535
http://localhost/t...ganizacniJednotka
  • 14110
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