About: Relevance of immunological variables in neuroborreliosis and multiple sclerosis

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aims were to investigate the frequency of intrathecal synthesis of specific antibodies against measles (M), rubella(R),and varicella zoster (Z)viruses(MRZ reaction) as a diagnostic marker between multiple sclerosis (MS) and neuroborreliosis (NB)groups and to postulate the most typical cerebrospinal fluid (CSF) variables profile of these entities. Three cohorts of patients were investigated :MS (n=42),NB (n=27) and other neurological diseases (OND) (n=15).Measles, rubella varicella zoster and borrelia specific IgG antibodies were measured by ELISA , Qalb as a marker of blood -CSF barrier function and specific antibody indices (AI) were calculated according to relevant formulae. IgG oligoclonal bands (OB) were detected by isoelectric focusing and immunoenzymatic staining. Results : Eighty- eight percent of MS patients had positive MRZ reaction and 26.2% had positive anti -borrelia AI. The aims were to investigate the frequency of intrathecal synthesis of specific antibodies against measles (M), rubella(R),and varicella zoster (Z)viruses(MRZ reaction) as a diagnostic marker between multiple sclerosis (MS) and neuroborreliosis (NB)groups and to postulate the most typical cerebrospinal fluid (CSF) variables profile of these entities. Three cohorts of patients were investigated :MS (n=42),NB (n=27) and other neurological diseases (OND) (n=15).Measles, rubella varicella zoster and borrelia specific IgG antibodies were measured by ELISA , Qalb as a marker of blood -CSF barrier function and specific antibody indices (AI) were calculated according to relevant formulae. IgG oligoclonal bands (OB) were detected by isoelectric focusing and immunoenzymatic staining. Results : Eighty- eight percent of MS patients had positive MRZ reaction and 26.2% had positive anti -borrelia AI. (en)
Title	Relevance of immunological variables in neuroborreliosis and multiple sclerosis Relevance of immunological variables in neuroborreliosis and multiple sclerosis (en)
skos:prefLabel	Relevance of immunological variables in neuroborreliosis and multiple sclerosis Relevance of immunological variables in neuroborreliosis and multiple sclerosis (en)
skos:notation	RIV/00216224:14110/05:00014962!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Štourač, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	540684
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/05:00014962
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MRZ reaction; multiple sclerosis; neuroborreliosis; immunological variables (en)
http://linked.open.../riv/klicoveSlovo	neuroborreliosis multiple sclerosis MRZ reaction immunological variables
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[50FCA712A6EB]
http://linked.open...i/riv/nazevZdroje	Acta Neurologica Scandinavica
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	112/2005
http://linked.open...iv/tvurceVysledku	Štourač, Pavel Adam, Pavel Bednářová, Jana
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	0001-6314
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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