About: Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review

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About: Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	V review jsou shrnuty vlastní a publikované výsledky naznačující vliv Schwannových buněk a endoneuriální extracelulární matrix na sortování regenerujících axonů v periferních nervech. (cs) Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses. Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses. (en)
Title	Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review (en) Schwannovy buňky a endoneuriální extracelulární matrix a jejich vliv na sortování regenerovaných axonů (cs)
skos:prefLabel	Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review (en) Schwannovy buňky a endoneuriální extracelulární matrix a jejich vliv na sortování regenerovaných axonů (cs)
skos:notation	RIV/00216224:14110/04:00010572!RIV09-GA0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/00/0407), Z(MSM 141100001)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Dubový, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	585555
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/04:00010572
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nerve regeneration; selective reinnervation; sensory and motor axons (en)
http://linked.open.../riv/klicoveSlovo	nerve regeneration selective reinnervation sensory and motor axons
http://linked.open...odStatuVydavatele	JP - Japonsko
http://linked.open...ontrolniKodProRIV	[8F567D8A00E6]
http://linked.open...i/riv/nazevZdroje	Anatomical Science International
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	79
http://linked.open...iv/tvurceVysledku	Dubový, Petr
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20141100001
issn	1447-6959
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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