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Description
  • We studied the development of antimony-resistant Leishmania infantum in natural vectors Lutzomyia longipalpis and Phlebotomus perniciosus to ascertain the risk of parasite transmission by sand flies. All three resistant strains produced fully mature late-stage infections in sand flies; moreover, the resistant phenotype was maintained after the passage through the vector. These results highlight the risk of circulation of resistant Leishmania strains and question the use of human drugs for treatment of dogs as Leishmania reservoirs.
  • We studied the development of antimony-resistant Leishmania infantum in natural vectors Lutzomyia longipalpis and Phlebotomus perniciosus to ascertain the risk of parasite transmission by sand flies. All three resistant strains produced fully mature late-stage infections in sand flies; moreover, the resistant phenotype was maintained after the passage through the vector. These results highlight the risk of circulation of resistant Leishmania strains and question the use of human drugs for treatment of dogs as Leishmania reservoirs. (en)
Title
  • Transmission Potential of Antimony-Resistant Leishmania Field Isolates
  • Transmission Potential of Antimony-Resistant Leishmania Field Isolates (en)
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  • Transmission Potential of Antimony-Resistant Leishmania Field Isolates
  • Transmission Potential of Antimony-Resistant Leishmania Field Isolates (en)
skos:notation
  • RIV/00216208:11310/14:10285222!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GA13-07500S)
http://linked.open...iv/cisloPeriodika
  • 10
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 51071
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/14:10285222
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • sandflies; glucantime; sensitivity; dogs; strains; infection; infantum; life-cycle; visceral leishmaniasis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C1FCC5647F42]
http://linked.open...i/riv/nazevZdroje
  • Antimicrobial Agents and Chemotherapy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 58
http://linked.open...iv/tvurceVysledku
  • Volf, Petr
  • Šeblová, Veronika
  • Gazanion, Elodie
  • Sereno, Denis
  • Pratlong, Francine
  • Ait-Oudhia, Khatima
  • Eddaikra, Naouel
  • Maia, Carla
  • Oury, Bruno
http://linked.open...ain/vavai/riv/wos
  • 000344157500078
issn
  • 0066-4804
number of pages
http://bibframe.org/vocab/doi
  • 10.1128/AAC.02406-13
http://localhost/t...ganizacniJednotka
  • 11310
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