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| Description
| - We have produced a draft genome sequence of another group dictyostelid, Dictyostelium purpureum, and compare it to the D. discoideum genome. The assembly (8.41 x coverage) comprises 799 scaffolds totaling 33.0 Mb, comparable to the D. discoideum genome size. Sequence comparisons suggest that these two dictyostelids shared a common ancestor approximately 400 million years ago. In spite of this divergence, most orthologs reside in small clusters of conserved synteny. Comparative analyses revealed a core set of orthologous genes that illuminate dictyostelid physiology, as well as differences in gene family content. Interesting patterns of gene conservation and divergence are also evident, suggesting function differences; some protein families, such as the histidine kinases, have undergone little functional change, whereas others, such as the polyketide synthases, have undergone extensive diversification. The abundant amino acid homopolymers encoded in both genomes are generally not found in homologous positions within proteins, so they are unlikely to derive from ancestral DNA triplet repeats. Genes involved in the social stage evolved more rapidly than others, consistent with either relaxed selection or accelerated evolution due to social conflict.
- We have produced a draft genome sequence of another group dictyostelid, Dictyostelium purpureum, and compare it to the D. discoideum genome. The assembly (8.41 x coverage) comprises 799 scaffolds totaling 33.0 Mb, comparable to the D. discoideum genome size. Sequence comparisons suggest that these two dictyostelids shared a common ancestor approximately 400 million years ago. In spite of this divergence, most orthologs reside in small clusters of conserved synteny. Comparative analyses revealed a core set of orthologous genes that illuminate dictyostelid physiology, as well as differences in gene family content. Interesting patterns of gene conservation and divergence are also evident, suggesting function differences; some protein families, such as the histidine kinases, have undergone little functional change, whereas others, such as the polyketide synthases, have undergone extensive diversification. The abundant amino acid homopolymers encoded in both genomes are generally not found in homologous positions within proteins, so they are unlikely to derive from ancestral DNA triplet repeats. Genes involved in the social stage evolved more rapidly than others, consistent with either relaxed selection or accelerated evolution due to social conflict. (en)
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| Title
| - Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
- Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum (en)
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| skos:prefLabel
| - Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
- Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum (en)
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| skos:notation
| - RIV/00216208:11310/11:10107601!RIV12-MSM-11310___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11310/11:10107601
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Amoebozoa; genome; evolution; dictyostelids; Comparative genomics (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Anjard, Christophe
- Babu, M Madan
- Barry, Kerrie
- Basu, Siddhartha
- Bruce, David
- Bushmanova, Yulia
- Chisholm, Rex L
- Coutinho, Pedro M
- Dalin, Eileen
- Dinh, Christopher
- Eichinger, Ludwig
- Eliáš, Marek
- Feasley, Christa L
- Fey, Petra
- Gaudet, Pascale
- Grigoriev, Igor V
- Henrissat, Bernard
- Huang, Eryong
- Katoh-Kurasawa, Mariko
- Kay, Robert R.
- Kuo, Alan
- Kuspa, Adam
- Lindquist, Erika
- Loomis, William F
- Parikh, Anup
- Putnam, Nicholas H
- Queller, David C
- Rivero, Francisco
- Saito, Tamao
- Salamov, Asaf
- Salerno, William
- Schaap, Pauline
- Schmutz, Jeremy
- Shapiro, Harris
- Shaulsky, Gad
- Strassmann, Joan E
- Sucgang, Richard
- Tian, Xiangjun
- Tu, Hank
- West, Christopher M
- van der Wel, Hanke
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://bibframe.org/vocab/doi
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| http://localhost/t...ganizacniJednotka
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