About: Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors     Goto   Sponge   Distinct   Permalink

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Description
  • Our aim was to determine the somatostatin (SSTR1-5) and estrogen receptor 1 (ER1) expression profile in 69 specimens of NFA. The expression of the receptors was determined by quantitative real time PCR. Results were normalized to the beta-glucuronidase housekeeping gene. With exceptions of SSTR4 and SSTR5, all other subtypes of receptors were expressed in the examined tumor specimens. The median relative quantification values were: 63.8% for SSTR1, 55.4% for SSTR2, 19.6% for SSTR3, 2.6% for SSTR4, 9.2% for SSTR5, and 75.4% for ER1.
  • Our aim was to determine the somatostatin (SSTR1-5) and estrogen receptor 1 (ER1) expression profile in 69 specimens of NFA. The expression of the receptors was determined by quantitative real time PCR. Results were normalized to the beta-glucuronidase housekeeping gene. With exceptions of SSTR4 and SSTR5, all other subtypes of receptors were expressed in the examined tumor specimens. The median relative quantification values were: 63.8% for SSTR1, 55.4% for SSTR2, 19.6% for SSTR3, 2.6% for SSTR4, 9.2% for SSTR5, and 75.4% for ER1. (en)
Title
  • Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors
  • Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors (en)
skos:prefLabel
  • Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors
  • Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors (en)
skos:notation
  • RIV/00216208:11150/13:10173513!RIV14-MZ0-11150___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(NT11344), S
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 89290
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/13:10173513
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • PCR; receptor; Somatostatin (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [44599D045905]
http://linked.open...i/riv/nazevZdroje
  • Klinická biochemie a metabolismus
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 21
http://linked.open...iv/tvurceVysledku
  • Beránek, Martin
  • Drastíková, Monika
  • Čáp, Jan
  • Gabalec, Filip
issn
  • 1210-7921
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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