About: The toxic effect of thioacetamide on rat liver in vitro

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Thioacetamid (TAA) is a hepatotoxin frequently used for experimental purposes, however the mechanism of its action has not been fully elucidated yet. Our results document that a profound reduction in the level of GSH precedes the rise in mitochondrial-dependent endogenous ROS, the disturbance in mitochondria metabolism, and cell death. Thioacetamid (TAA) is a hepatotoxin frequently used for experimental purposes, however the mechanism of its action has not been fully elucidated yet. Our results document that a profound reduction in the level of GSH precedes the rise in mitochondrial-dependent endogenous ROS, the disturbance in mitochondria metabolism, and cell death. (en)
Title	The toxic effect of thioacetamide on rat liver in vitro The toxic effect of thioacetamide on rat liver in vitro (en)
skos:prefLabel	The toxic effect of thioacetamide on rat liver in vitro The toxic effect of thioacetamide on rat liver in vitro (en)
skos:notation	RIV/00216208:11150/10:10080076!RIV11-GA0-11150___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP305/09/P145), Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Roušar, Tomáš Staňková, Pavla Kremláček, Jan Červinková, Zuzana Kučera, Otto Endlicher, René
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	293154
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/10:10080076
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ros; mitochondria; oxidative stress; rat hepatocytes; Thioacetamide (en)
http://linked.open.../riv/klicoveSlovo	rat hepatocytes ros Thioacetamide mitochondria oxidative stress
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[F37BE6364F4F]
http://linked.open...i/riv/nazevZdroje	Toxicology in Vitro
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of mitochondria in toxic liver injury and in liver regeneration
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Roušar, Tomáš Kučera, Otto Lotková, Halka Staňková, Pavla Červinková, Zuzana Endlicher, René
http://linked.open...ain/vavai/riv/wos	000285124500008
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	0887-2333
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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