About: Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion

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About: Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We explored the differentiation potential of region-specific neural stem/progenitor cells (NS/PCs) isolated from dorsal telencephalons of mouse embryos in vitro and after transplantation into a lesioned rat brain. Transplanted D6/GFP NS/PCs gave rise primarily to NeuN/MAP-2-positive neurons and were able to generate action potentials. The importance of the finding lies in proposing a new direction in CNS tissue regeneration. We explored the differentiation potential of region-specific neural stem/progenitor cells (NS/PCs) isolated from dorsal telencephalons of mouse embryos in vitro and after transplantation into a lesioned rat brain. Transplanted D6/GFP NS/PCs gave rise primarily to NeuN/MAP-2-positive neurons and were able to generate action potentials. The importance of the finding lies in proposing a new direction in CNS tissue regeneration. (en)
Title	Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion (en)
skos:prefLabel	Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion (en)
skos:notation	RIV/00216208:11130/10:6187!RIV11-GA0-11130___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(GA305/09/0717), P(GD309/08/H079), P(LC554), S, Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Prajerová, Iva Anděrová, Miroslava Chvátal, Alexandr Honsa, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	274509
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/10:6187
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Ischemia; Ion channels; Patch-clamp; Injury and repair; central-nervous-system; radial glial-cells; rat spinal-cord; neocortical pyramidal neurons; gated k+ channels; stem-cells; progenitor cells; precursor cells; in-vitro; neurosphere cultures (en)
http://linked.open.../riv/klicoveSlovo	Ischemia central-nervous-system rat spinal-cord Patch-clamp progenitor cells stem-cells precursor cells Injury and repair gated k+ channels neocortical pyramidal neurons neurosphere cultures radial glial-cells in-vitro Ion channels
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2E033251F002]
http://linked.open...i/riv/nazevZdroje	Cellular and Molecular Neurobiology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	PhD program in neuroscience Center for Cell Therapy and Tissue Repair Neuroscience Centre Induction of neuro- and gliogenesis in rat brain after ischemia - the role of morphogenes and growth factors in the nervous tissue regeneration.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Anděrová, Miroslava Chvátal, Alexandr Honsa, Pavel Prajerová, Iva
http://linked.open...ain/vavai/riv/wos	000275704800005
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0272-4340
number of pages	20 (xsd:int)
http://localhost/t...ganizacniJednotka	11130

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