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rdf:type
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rdfs:seeAlso
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Description
| - The aim of the study is to compare the effects of new fluorinated taxanes SB-T-12851, SB-T-12852, SB-T-12853, and SB-T-12854 with those of the classical taxane paclitaxel and novel non-fluorinated taxane SB-T-1216 on cancer cells. Paclitaxel -sensitive MDA-MB-435 and paclitaxel-resistant NCI/ADR-RES human cancer cell lines were used. The new fluorinated taxanes appear to use the same or similar mechanisms of cell death induction as compared with SB-T-1216 and paclitaxel. New fluorinated and non-fluorinated taxanes are more effective against drug-resistant cancer cells than paclitaxel.
- The aim of the study is to compare the effects of new fluorinated taxanes SB-T-12851, SB-T-12852, SB-T-12853, and SB-T-12854 with those of the classical taxane paclitaxel and novel non-fluorinated taxane SB-T-1216 on cancer cells. Paclitaxel -sensitive MDA-MB-435 and paclitaxel-resistant NCI/ADR-RES human cancer cell lines were used. The new fluorinated taxanes appear to use the same or similar mechanisms of cell death induction as compared with SB-T-1216 and paclitaxel. New fluorinated and non-fluorinated taxanes are more effective against drug-resistant cancer cells than paclitaxel. (en)
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Title
| - Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells
- Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells (en)
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skos:prefLabel
| - Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells
- Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells (en)
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skos:notation
| - RIV/00216208:11120/11:00003156!RIV12-MZ0-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA301/09/0362), P(NR9426)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/11:00003156
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Cell death; paclitaxel; taxanes; fluorinated taxanes; caspases (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Investigational New Drugs
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kovář, Jan
- Neubauerová, Jitka
- Němcová-Fürstová, Vlasta
- Vobořilová, Jana
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1007/s10637-009-9368-8
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http://localhost/t...ganizacniJednotka
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