About: Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1007/s10637-009-9368-8
Description	The aim of the study is to compare the effects of new fluorinated taxanes SB-T-12851, SB-T-12852, SB-T-12853, and SB-T-12854 with those of the classical taxane paclitaxel and novel non-fluorinated taxane SB-T-1216 on cancer cells. Paclitaxel -sensitive MDA-MB-435 and paclitaxel-resistant NCI/ADR-RES human cancer cell lines were used. The new fluorinated taxanes appear to use the same or similar mechanisms of cell death induction as compared with SB-T-1216 and paclitaxel. New fluorinated and non-fluorinated taxanes are more effective against drug-resistant cancer cells than paclitaxel. The aim of the study is to compare the effects of new fluorinated taxanes SB-T-12851, SB-T-12852, SB-T-12853, and SB-T-12854 with those of the classical taxane paclitaxel and novel non-fluorinated taxane SB-T-1216 on cancer cells. Paclitaxel -sensitive MDA-MB-435 and paclitaxel-resistant NCI/ADR-RES human cancer cell lines were used. The new fluorinated taxanes appear to use the same or similar mechanisms of cell death induction as compared with SB-T-1216 and paclitaxel. New fluorinated and non-fluorinated taxanes are more effective against drug-resistant cancer cells than paclitaxel. (en)
Title	Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells (en)
skos:prefLabel	Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells (en)
skos:notation	RIV/00216208:11120/11:00003156!RIV12-MZ0-11120___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA301/09/0362), P(NR9426)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Neubauerová, Jitka Kovář, Jan Němcová-Fürstová, Vlasta Vobořilová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	189374
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/11:00003156
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cell death; paclitaxel; taxanes; fluorinated taxanes; caspases (en)
http://linked.open.../riv/klicoveSlovo	caspases Cell death fluorinated taxanes paclitaxel taxanes
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[FA520978620E]
http://linked.open...i/riv/nazevZdroje	Investigational New Drugs
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of caspase-2 in apoptosis induction by taxanes in breast cancer cells Influence of transport and metabolism of used and novel taxanes on effects and their mechanisms in patients and tumor cell lines
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	29
http://linked.open...iv/tvurceVysledku	Kovář, Jan Neubauerová, Jitka Němcová-Fürstová, Vlasta Vobořilová, Jana
http://linked.open...ain/vavai/riv/wos	000289526400002
issn	0167-6997
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s10637-009-9368-8
http://localhost/t...ganizacniJednotka	11120

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 81 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software