Attributes | Values |
---|
rdf:type
| |
Description
| - The aim of this study was to compare the expression of proteins potentially involved in non-transferrin iron transport across membranes (DMT1, Dcytb, ferroportin, hephaestin, and ceruloplasmin) in various types of human cells (Caco-2, K562 and HEP-G2) under extracellular iron deficiency and excess of extracellular non-transferrin iron. We demonstrated that changes in iron availability, i.e. iron deficiency and iron excess, affect the expression of DMT1, Dcytb, ferroportin, hephaestin and ceruloplasmin on mRNA as well as on protein level in a cell type-specific manner.
- The aim of this study was to compare the expression of proteins potentially involved in non-transferrin iron transport across membranes (DMT1, Dcytb, ferroportin, hephaestin, and ceruloplasmin) in various types of human cells (Caco-2, K562 and HEP-G2) under extracellular iron deficiency and excess of extracellular non-transferrin iron. We demonstrated that changes in iron availability, i.e. iron deficiency and iron excess, affect the expression of DMT1, Dcytb, ferroportin, hephaestin and ceruloplasmin on mRNA as well as on protein level in a cell type-specific manner. (en)
- Cílem práce bylo porovnat expresi proteinů účastnících se transportu netransferinového železa přes membrány (DMT1, Dcytb, ferroportin, hephaestin, a ceruloplasmin) u různých typů lidských buněk (Caco-2, K562 and HEP-G2) pod vlivem deprivace a nadbytku extracelulárního netransferinového železa. Ukázali jsme, že změny v dostupnosti železa, tj. deprivace železa a nadbytek železa, ovlivňují expresi DMT1, Dcytb, ferroportinu, hephaestinu a ceruloplasminu na úrovni mRNA i proteinů v závislosti na daném typu buněk. (cs)
|
Title
| - Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess
- Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess (en)
- Rozdílná exprese genů zúčastněných v transportu netransferinového železa přes plazmatickou membránu u různých typů buněk pod vlivem deprivace a nadbytku železa (cs)
|
skos:prefLabel
| - Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess
- Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess (en)
- Rozdílná exprese genů zúčastněných v transportu netransferinového železa přes plazmatickou membránu u různých typů buněk pod vlivem deprivace a nadbytku železa (cs)
|
skos:notation
| - RIV/00216208:11120/09:00000488!RIV09-MSM-11120___
|
http://linked.open...avai/riv/aktivita
| |
http://linked.open...avai/riv/aktivity
| |
http://linked.open...iv/cisloPeriodika
| |
http://linked.open...vai/riv/dodaniDat
| |
http://linked.open...aciTvurceVysledku
| |
http://linked.open.../riv/druhVysledku
| |
http://linked.open...iv/duvernostUdaju
| |
http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/09:00000488
|
http://linked.open...riv/jazykVysledku
| |
http://linked.open.../riv/klicovaSlova
| - Non-transferrin iron transport; DMT1; Dcytb; Ferroportin; Hephaestin; Ceruloplasmin (en)
|
http://linked.open.../riv/klicoveSlovo
| |
http://linked.open...odStatuVydavatele
| |
http://linked.open...ontrolniKodProRIV
| |
http://linked.open...i/riv/nazevZdroje
| - Molecular and Cellular Biochemistry
|
http://linked.open...in/vavai/riv/obor
| |
http://linked.open...ichTvurcuVysledku
| |
http://linked.open...cetTvurcuVysledku
| |
http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Horák, Jiří
- Kovář, Jan
- Neubauerová, Jitka
- Dostalíková-Čimburová, Markéta
- Balušíková, Kamila
|
http://linked.open...ain/vavai/riv/wos
| |
http://linked.open...n/vavai/riv/zamer
| |
issn
| |
number of pages
| |
http://localhost/t...ganizacniJednotka
| |