About: Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells     Goto   Sponge   Distinct   Permalink

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  • The death induced by the taxanes in the studied brest cancer cells can be characterized as an apoptosis-like death, including caspase-3 and caspase-9 activation but not oligonucleosomal DNA fragmentation. However, the mechanism of death induction by the taxanes in sensitive MDA-MB-435 cells and resistant NCI-ADR-RES cells differ. Cytochrome c is released from the mitochondria in resistant but not in sensitive cells.
  • The death induced by the taxanes in the studied brest cancer cells can be characterized as an apoptosis-like death, including caspase-3 and caspase-9 activation but not oligonucleosomal DNA fragmentation. However, the mechanism of death induction by the taxanes in sensitive MDA-MB-435 cells and resistant NCI-ADR-RES cells differ. Cytochrome c is released from the mitochondria in resistant but not in sensitive cells. (en)
  • Smrt indukovanou taxany ve studovaných buňkách nádoru prsu lze charakterizovat jako apoptóze podobnou smrt, která zahrnuje aktivaci kaspázy 3 a kaspázy 9, ale nezahrnuje oligonukleozomální fragmentaci DNA. Mechanismus indukce smrti taxany u senzitivních MDA-MB-435 buněk a rezistentních NCI-ADR-RES buněk se však liší. Cytochrom c se uvolňuje zmitochondrií vrezistentních, ale ne v senzitivních buňkách. (cs)
Title
  • Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells
  • Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells (en)
  • Buněčná smrt indukovaná taxany vbuňkách nádoru prsu: cytochrom c se uvolňuje vrezistentních, ale ne v senzitivních buňkách (cs)
skos:prefLabel
  • Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells
  • Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells (en)
  • Buněčná smrt indukovaná taxany vbuňkách nádoru prsu: cytochrom c se uvolňuje vrezistentních, ale ne v senzitivních buňkách (cs)
skos:notation
  • RIV/00216208:11120/05:00009566!RIV06-MZ0-11120___
http://linked.open.../vavai/riv/strany
  • 4215;4224
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  • P(NL7567)
http://linked.open...iv/cisloPeriodika
  • 6B
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  • 514596
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  • RIV/00216208:11120/05:00009566
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  • Death; Induced; Taxanes; Brest; Cancer; Cells; Cytochrome; Released; Resistant; Sensitive; Cells (en)
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http://linked.open...odStatuVydavatele
  • GR - Řecká republika
http://linked.open...ontrolniKodProRIV
  • [E726279D1903]
http://linked.open...i/riv/nazevZdroje
  • Anticancer Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Kovář, Jan
issn
  • 0250-7005
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http://localhost/t...ganizacniJednotka
  • 11120
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