About: Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells     Goto   Sponge   Distinct   Permalink

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Description
  • The regulation of PrP(C) expression in differentiating MEL cells mimics the pattern detected on mouse erythroid precursors in vivo. Decrease of PrP(C) protein expression during MEL cell maturation is not regulated on transcriptional level. The efficient silencing of PrP(C) levels, despite not affecting MEL cell differentiation, enables created MEL lines to be used for studies of PrP(C) cellular function.
  • The regulation of PrP(C) expression in differentiating MEL cells mimics the pattern detected on mouse erythroid precursors in vivo. Decrease of PrP(C) protein expression during MEL cell maturation is not regulated on transcriptional level. The efficient silencing of PrP(C) levels, despite not affecting MEL cell differentiation, enables created MEL lines to be used for studies of PrP(C) cellular function. (en)
Title
  • Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells
  • Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells (en)
skos:prefLabel
  • Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells
  • Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells (en)
skos:notation
  • RIV/00216208:11110/11:8961!RIV12-GA0-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA310/08/0878), S, Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 199028
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/11:8961
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • prion; hexamethylene bisacetamide; gene expression; blood cells; iron uptake; PRPC; dexamethasone (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [51E9BBC18FBF]
http://linked.open...i/riv/nazevZdroje
  • PLoS One
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Holada, Karel
  • Panigaj, Martin
  • Glier, Hana
  • Wildová, Marcela
http://linked.open...ain/vavai/riv/wos
  • 000294686100051
http://linked.open...n/vavai/riv/zamer
issn
  • 1932-6203
number of pages
http://localhost/t...ganizacniJednotka
  • 11110
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